GHITM 抗体 (AA 1-345)
-
- 抗原 See all GHITM 抗体
- GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))
-
抗原表位
- AA 1-345
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This GHITM antibody is un-conjugated
-
应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- Anti-GHITM Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-GHITM Antibody Picoband® (ABIN7599294). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human GHITM recombinant protein (Position: M1-K345).
- 亚型
- IgG
- Top Product
- Discover our top product GHITM Primary Antibody
-
anti-Growth Hormone Inducible Transmembrane Protein (GHITM) (AA 293-345) antibody
GHITM 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Inducible Transmembrane Protein (GHITM) (Internal Region) antibodyVerified GHITM 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Growth Hormone Inducible Transmembrane Protein (GHITM) antibodyGHITM 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Inducible Transmembrane Protein (GHITM) (N-Term) antibodyGHITM 适用: 人 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Inducible Transmembrane Protein (GHITM) (AA 117-127) antibodyVerified GHITM 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Growth Hormone Inducible Transmembrane Protein (GHITM) (Middle Region) antibodyGHITM 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 2/23/2021. 2. Lisak, D. A., Schacht, T., Enders, V., Habicht, J., Kiviluoto, S., Scheider, J., Henke, N., Bultynck, G., Methner, A. The transmembrane Bax inhibitor motif (TMBIM) containing protein family: tissue expression, intracellular localization and effects on the ER Ca(2+)-filling state. Biochim. Biophys. Acta 1853: 2104-2114, 2015. 3. Oka, T., Sayano, T., Tamai, S., Yokota, S., Kato, H., Fujii, G., Mihara, K. Identification of a novel protein MICS1 that is involved in maintenance of mitochondrial morphology and apoptotic release of cytochrome c. Molec. Biol. Cell 19: 2597-2608, 2008. - 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
- 抗原
- GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))
- 别名
- GHITM (GHITM 产品)
- 背景
-
Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7
Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.
Background: Growth hormone-inducible transmembrane protein (GHITM), also known as transmembrane BAX inhibitor motif containing protein 5 (TMBIM5), is a protein that in humans is encoded by the GHITM gene on chromosome 10. GHITM, also known asMICS1, TMBIM5 orDERP2, is a mitochondrial protein which localizes in the inner membrane.GHITM is involved in mitochondrial morphology in specific cristae structures and the apoptotic release of cytochrome c from the mitochondria. The gene of GHITM maps to chromosome 10q23.1, and encodes a 345-amino-acid protein with a calculated molecular mass of 37 kDa. The apparent molecular weight has been reported to be 42 kDa, the increased size in the protein may be due to post-translational modifications. GHITM can be cleaved into smaller forms of 23-27 kDa.
- 分子量
- 37 kDa
- 基因ID
- 27069
- UniProt
- Q9H3K2
- 途径
- SARS-CoV-2 Protein Interactome
-
