CX3CR1 抗体 (AA 1-345)
Quick Overview for CX3CR1 抗体 (AA 1-345) (ABIN7599293)
抗原
See all CX3CR1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-345
-
原理
- Anti-CX3CR1 Antibody
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-CX3CR1 Antibody Picoband® (ABIN7599293). Tested in ELISA, Flow Cytometry, IHC applications. This antibody reacts with Human.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human CX3CR1 recombinant protein (Position: M1-H345).
-
亚型
- IgG
-
-
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 151-250) antibody
CX3CR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 7-20), (Extracellular) antibodyCX3CR1 适用: 小鼠 WB, FACS, IHC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (Extracellular Domain) antibodyCX3CR1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 1-36) antibodyCX3CR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 298-351) antibodyCX3CR1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (N-Term) antibodyCX3CR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 2-21) antibodyCX3CR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (N-Term) antibodyCX3CR1 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 34-47) antibodyVerified CX3CR1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 1-355) antibodyCX3CR1 适用: 人 IF 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
-
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Combadiere, C., Feumi, C., Raoul, W., Keller, N., Rodero, M., Pezard, A., Lavalette, S., Houssier, M., Jonet, L., Picard, E., Debre, P., Sirinyan, M., Deterre, P., Ferroukhi, T., Cohen, S.-Y., Chauvaud, D., Jeanny, J.-C., Chemtob, S., Behar-Cohen, F., Sennlaub, F. CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration. J. Clin. Invest. 117: 2920-2928, 2007. 2. Faure, S., Meyer, L., Costagliola, D., Vaneensberghe, C., Genin, E., Autran, B., French ALT and IMMUNOCO Study Groups, Delfraisay, J.-F., SEROCO Study Group, McDermott, D. H., Murphy, P. M., Debre, P., Theodorou, I., Combadiere, C. Rapid progression to AIDS in HIV+ individuals with a structural variant of the chemokine receptor CX(3)CR1. Science 287: 2274-2277, 2000. 3. Feldman, G. J., Parvizi, J., Levenstien, M., Scott, K., Erickson, J. A., Fortina, P., Devoto, M., Peters, C. L. Developmental dysplasia of the hip: linkage mapping and whole exome sequencing identify a shared variant in CX3CR1 in all affected members of a large multigeneration family. J. Bone Miner. Res. 28: 2540-2549, 2013. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
-
别名
- CX3CR1
-
背景
-
Synonyms: Merlin, Moesin-ezrin-radixin-like protein, Neurofibromin-2, Schwannomerlin, Schwannomin, NF2, SCH
Tissue Specificity: Widely expressed. Isoform 1 and isoform 3 are predominant. Isoform 4, isoform 5 and isoform 6 are expressed moderately. Isoform 8 is found at low frequency. Isoform 7, isoform 9 and isoform 10 are not expressed in adult tissues, with the exception of adult retina expressing isoform 10. Isoform 9 is faintly expressed in fetal brain, heart, lung, skeletal muscle and spleen. Fetal thymus expresses isoforms 1, 7, 9 and 10 at similar levels.
Background: CX3C chemokine receptor 1 (CX3CR1) also known as the fractalkine receptor or G-protein coupled receptor 13 (GPR13) is a protein that in humans is encoded by the CX3CR1 gene. Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
-
分子量
- 69 kDa
-
基因ID
- 1524
-
UniProt
- P49238
-
途径
- Cellular Response to Molecule of Bacterial Origin
抗原
-
