NANS 抗体 (AA 1-341)
Quick Overview for NANS 抗体 (AA 1-341) (ABIN7599289)
抗原
See all NANS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-341
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原理
- Anti-NANS Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-NANS Antibody Picoband® (ABIN7599289). Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NANS recombinant protein (Position: M1-E341). Human NANS shares 96.2% amino acid (aa) sequence identity with mouse NANS.
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亚型
- IgG
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anti-N-Acetylneuraminic Acid Synthase (NANS) (AA 132-259) antibody
NANS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Acetylneuraminic Acid Synthase (NANS) (AA 260-359) antibodyNANS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G6 unconjugated
anti-N-Acetylneuraminic Acid Synthase (NANS) (Center) antibodyNANS 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-N-Acetylneuraminic Acid Synthase (NANS) (AA 1-359) antibodyNANS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-N-Acetylneuraminic Acid Synthase (NANS) (AA 260-359) antibodyNANS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Acetylneuraminic Acid Synthase (NANS) (AA 1-245) antibodyNANS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT2E7 unconjugated
anti-N-Acetylneuraminic Acid Synthase (NANS) antibodyNANS 适用: 人 WB, EIA 宿主: 小鼠 Monoclonal AT1G6 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL
1. Camera, G., Camera, A., Gatti, R. Sponastrime dysplasia: report on two siblings with mental retardation. Pediat. Radiol. 23: 611-614, 1993. 2. Genevieve, D., Heron, D., El Ghouzzi, V., Prost-Squarcioni, C., Le Merrer, M., Jacquette, A., Sanlaville, D., Pinton, F., Villeneuve, N., Kalifa, G., Munnich, A., Cormier-Daire, V. Exclusion of the dymeclin and PAPSS2 genes in a novel form of spondyloepimetaphyseal dysplasia and mental retardation. Europ. J. Hum. Genet. 13: 541-546, 2005. 3. Lawrence, S. M., Huddleston, K. A., Pitts, L. R., Nguyen, N., Lee, Y. C., Vann, W. F., Coleman, T. A., Betenbaugh, M. J. Cloning and expression of the human N-acetylneuraminic acid phosphate synthase gene with 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid biosynthetic ability. J. Biol. Chem. 275: 17869-17877, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NANS (N-Acetylneuraminic Acid Synthase (NANS))
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别名
- NANS
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背景
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Synonyms: NANS, SAS, Sialic acid synthase, N-acetylneuraminate synthase, EC 2.5.1.56, N-acetylneuraminate-9-phosphate synthase, EC 2.5.1.57, N-acetylneuraminic acid phosphate synthase, N-acetylneuraminic acid synthase
Background: Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene. This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
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分子量
- 38 kDa
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基因ID
- 54187
抗原
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