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FOSB 抗体 (AA 1-332)

This anti-FOSB antibody is a 兔 多克隆 antibody detecting FOSB in ELISA, IHC, IF 和 ICC. Suitable for 人.
产品编号 ABIN7599279
发货至: 中国

Quick Overview for FOSB 抗体 (AA 1-332) (ABIN7599279)

抗原

See all FOSB 抗体
FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

适用

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宿主

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克隆类型

  • 55
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多克隆

标记

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This FOSB antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 19
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    AA 1-332

    原理

    Anti-Fos B/FOSB Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Fos B/FOSB Antibody Picoband® (ABIN7599279). Tested in ELISA, IF, IHC, ICC applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human FOSB recombinant protein (Position: M1-S332).

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Kelz, M. B., Chen, J., Carlezon, W. A., Jr., Whisler, K., Gilden, L., Beckmann, A. M., Steffen, C., Zhang, Y.-J., Marotti, L., Self, D. W., Tkatch, T., Baranauskas, G., Surmeier, D. J., Neve, R. L., Duman, R. S., Picciotto, M. R., Nestler, E. J.Expression of the transcription factor delta-FosB in the brain controls sensitivity to cocaine.Nature 401: 272-276, 1999. 2. Martin-Gallardo, A., McCombie, W. R., Gocayne, J. D., FitzGerald, M. G., Wallace, S., Lee, B. M. B., Lamerdin, J., Trapp, S., Kelley, J. M., Liu, L.-I., Dubnick, M., Johnston-Dow, L. A., Kerlavage, A. R., de Jong, P., Carrano, A., Fields, C., Venter, J. C.Automated DNA sequencing and analysis of 106 kilobases from human chromosome 19q13.3.Nature Genet. 1: 34-39, 1992. 3. Nakabeppu, Y., Nathans, D.A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity.Cell 64: 751-759, 1991.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

    别名

    FOSB

    背景

    Synonyms: Vitamin K-dependent protein S, PROS1, PROS

    Tissue Specificity: Plasma.

    Background: FOSB, FBJ murine osteosarcoma viral oncogene homolog B, is a protein that, in humans, is encoded by the FOSB gene. FOSB is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. The FOSB gene is mapped to 19q13.32. Delta FOSB is a truncated splice variant of FOSB. Delta FosB has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. Delta FosB also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.

    分子量

    75 kDa

    基因ID

    2354

    UniProt

    P53539
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