CXCR3 抗体 (AA 1-326)
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北京 101111
Quick Overview for CXCR3 抗体 (AA 1-326) (ABIN7599273)
抗原
See all CXCR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-326
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原理
- Anti-Cxcr3 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Cxcr3 Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Cxcr3 recombinant protein (Position: M1-E326).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
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别名
- Cxcr3
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背景
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Background: Chemokine receptor CXCR3 is a Galphai protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183. It is mapped to Xq13.1. CXCR3 is expressed on malignant B cells from chronic lymphoproliferative disorders, particularly in patients with CLL, and represents a fully functional receptor involved in chemotaxis of malignant B lymphocytes. It is found that in the absence of known etiologic agents, CXCR3 represents a novel target for therapeutic interference early in type 1 diabetes. CXCR3 signaling is associated with MG pathogenesis and proposed that and CXCR3 may serve as novel drug targets to treat MG. CXCR3A and CXCR3B are involved in the chemotactic and vascular effects of CXCL4L1.
Gene Full Name: C-X-C motif chemokine receptor 3
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分子量
- 46 kDa
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基因ID
- 12766
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UniProt
- O88410
抗原
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