CXCR3 抗体 (AA 1-326)
Quick Overview for CXCR3 抗体 (AA 1-326) (ABIN7599273)
抗原
See all CXCR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-326
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原理
- Anti-Cxcr3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Cxcr3 Antibody Picoband® (ABIN7599273). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Cxcr3 recombinant protein (Position: M1-E326).
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亚型
- IgG
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anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) antibody
CXCR3 适用: 人 FACS, WB, ELISA, IHC 宿主: 小鼠 Monoclonal 5C10E6 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 301-367) antibodyCXCR3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (C-Term) antibodyVerified CXCR3 适用: 人 FACS, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-368) antibodyCXCR3 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 4-50) antibodyCXCR3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-100) antibodyCXCR3 适用: 人, 小鼠 FACS, WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (Internal Region) antibodyCXCR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (C-Term) antibodyCXCR3 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 140-167) antibodyCXCR3 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB23384 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 147-175), (Middle Region) antibodyCXCR3 适用: 人 FACS, WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Trentin, L., Agostini, C., Facco, M., Piazza, F., Perin, A., Siviero, M., Gurrieri, C., Galvan, S., Adami, F., Zambello, R., Semenzato, G. The chemokine receptor CXCR3 is expressed on malignant B cells and mediates chemotaxis. J. Clin. Invest. 104: 115-121, 1999. 2. Frigerio, S., Junt, T., Lu, B., Gerard, C., Zumsteg, U., Hollander, G. A., Piali, L. Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis. Nature Med. 8: 1414-1420, 2002. 3. Feferman, T., Maiti, P. K., Berrih-Aknin, S., Bismuth, J., Bidault, J., Fuchs, S., Souroujon, M. C. Overexpression of IFN-induced protein 10 and its receptor CXCR3 in myasthenia gravis. J. Immun. 174: 5324-5331, 2005. 4. Struyf, S., Salogni, L., Burdick, M. D., Vandercappellen, J., Gouwy, M., Noppen, S., Proost, P., Opdenakker, G., Parmentier, M., Gerard, C., Sozzani, S., Strieter, R. M., Van Damme, J. Angiostatic and chemotactic activities of the CXC chemokine CXCL4L1 (platelet factor-4 variant) are mediated by CXCR3. Blood 117: 480-488, 2011. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
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别名
- Cxcr3
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背景
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Synonyms: Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, TNF-R1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, p55, p60, CD120a, Tumor necrosis factor receptor superfamily member 1A, membrane form, Tumor necrosis factor-binding protein 1, TBPI, TNFRSF1A, TNFAR, TNFR1
Tissue Specificity: Activated T-cells. Highly expressed on tonsillar T-cells, which are closely associated with B-cells in the apical light zone of germinal centers, the site of terminal B- cell maturation. Expressed at lower levels in thymus, lung, lymph node and peripheral blood leukocytes. Expressed in the medulla of fetal and newborn thymus.
Background: Chemokine receptor CXCR3 is a Galphai protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183. It is mapped to Xq13.1. CXCR3 is expressed on malignant B cells from chronic lymphoproliferative disorders, particularly in patients with CLL, and represents a fully functional receptor involved in chemotaxis of malignant B lymphocytes. It is found that in the absence of known etiologic agents, CXCR3 represents a novel target for therapeutic interference early in type 1 diabetes. CXCR3 signaling is associated with MG pathogenesis and proposed that and CXCR3 may serve as novel drug targets to treat MG. CXCR3A and CXCR3B are involved in the chemotactic and vascular effects of CXCL4L1.
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分子量
- 46 kDa
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基因ID
- 12766
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UniProt
- O88410
抗原
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