RAD51AP1 抗体 (AA 1-303)
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北京 101111
Quick Overview for RAD51AP1 抗体 (AA 1-303) (ABIN7599248)
抗原
See all RAD51AP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-303
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原理
- Anti-RAD51AP1 Antibody
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产品特性
- Anti-RAD51AP1 Antibody (ABIN7599248). Tested in WB, IF, IHC, ICC, Flow Cytometry, ELISA applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RAD51AP1 recombinant protein (Position: M1-K303).
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亚型
- IgG
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anti-RAD51-Interacting Protein (RAD51AP1) (C-Term) antibody
Verified RAD51AP1 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-RAD51-Interacting Protein (RAD51AP1) (AA 1-335) antibodyRAD51AP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-RAD51-Interacting Protein (RAD51AP1) (AA 1-335) antibodyRAD51AP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-RAD51-Interacting Protein (RAD51AP1) (AA 215-264) antibodyRAD51AP1 适用: 人, 犬, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51-Interacting Protein (RAD51AP1) (AA 143-192) antibodyRAD51AP1 适用: 人, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RAD51AP1 (RAD51-Interacting Protein (RAD51AP1))
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别名
- RAD51AP1
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背景
- The RAD51AP1 gene encodes a protein known as RAD51-associated protein 1, which plays a crucial role in homologous recombination, a DNA repair pathway essential for maintaining genomic integrity. RAD51AP1 interacts with RAD51, a key protein involved in homologous recombination, and promotes the assembly of RAD51 nucleoprotein filaments on single-stranded DNA, facilitating the search for homologous sequences and strand exchange. This process is vital for repairing DNA double-strand breaks and stalled replication forks, as well as for meiotic recombination and telomere maintenance. Dysregulation of RAD51AP1 expression or function has been implicated in cancer development and progression, as defects in homologous recombination can lead to genomic instability and oncogenesis. Understanding the molecular mechanisms underlying RAD51AP1-mediated homologous recombination is crucial for deciphering its role in DNA repair and genome maintenance, as well as for developing targeted therapies for cancer and other diseases associated with DNA damage.
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分子量
- 38 kDa
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基因ID
- 10635
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UniProt
- Q96B01
抗原
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