PPP1R3B 抗体 (AA 1-285)
Quick Overview for PPP1R3B 抗体 (AA 1-285) (ABIN7599215)
抗原
See all PPP1R3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-285
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原理
- Anti-PPP1R3B Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PPP1R3B Antibody Picoband® (ABIN7599215). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PPP1R3B recombinant protein (Position: M1-Y285).
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亚型
- IgG
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anti-Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B) (AA 1-285), (Regulatory Subunit 3B) antibody
PPP1R3B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B) (AA 1-285) antibodyPPP1R3B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B) (AA 40-89) antibodyPPP1R3B 适用: 人, 小鼠, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B) (AA 1-140) antibodyPPP1R3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B) (N-Term) antibodyPPP1R3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Doherty, M. J., Moorhead, G., Morrice, N., Cohen, P., Cohen, P. T. W. Amino acid sequence and expression of hepatic glycogen-binding (G-L)-subunit of protein phosphatase-1. FEBS Lett. 375: 294-298, 1995. 2. Dunn, J. S., Mlynarski, W. M., Pezzoles, M. G., Borowiec, M., Powers, C., Krolewski, A. S., Doria, A. Examination of PPP1R3B as a candidate gene for the type 2 diabetes and MODY loci on chromosome 8p23. Ann. Hum. Genet. 70: 587-593, 2006. 3. Munro, S., Cuthbertson, D. J. R., Cunningham, J., Sales, M., Cohen, P. T. W. Human skeletal muscle expresses a glycogen-targeting subunit of PP1 that is identical to the insulin-sensitive glycogen-targeting subunit G-L of liver. Diabetes 51: 591-598, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PPP1R3B (Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B))
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别名
- PPP1R3B
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背景
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Synonyms: One cut domain family member 2, Hepatocyte nuclear factor 6-beta, HNF-6-beta, One cut homeobox 2, Transcription factor ONECUT-2, OC-2, ONECUT2, HNF6B
Tissue Specificity: Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines.
Background: This gene encodes the catalytic subunit of the serine/theonine phosphatase, protein phosphatase-1. The encoded protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein.
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分子量
- 33 kDa
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基因ID
- 79660
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途径
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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