GATM 抗体 (AA 1-279)
Quick Overview for GATM 抗体 (AA 1-279) (ABIN7599207)
抗原
See all GATM 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-279
-
原理
- Anti-GATM Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-GATM Antibody Picoband® (ABIN7599207). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human GATM recombinant protein (Position: M1-E279). Human GATM shares 95.3% and 95% amino acid (aa) sequence identity with mouse and rat GATM, respectively.
-
亚型
- IgG
-
-
anti-Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) antibody
GATM 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) (Middle Region) antibodyGATM 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) (AA 124-423) antibodyGATM 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) (AA 124-423) antibodyGATM 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) (AA 1-423) antibodyGATM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) antibodyGATM 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) antibodyGATM 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) (AA 251-300) antibodyGATM 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Bat, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) (AA 1-100) antibodyGATM 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H7 unconjugated
anti-Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) (AA 350-378), (C-Term) antibodyGATM 适用: 人 WB 宿主: 兔 Polyclonal RB41023 unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Battini, R., Leuzzi, V., Carducci, C., Tosetti, M., Bianchi, M. C., Item, C. B., Stockler-Ipsiroglu, S., Cioni, G. Creatine depletion in a new case with AGAT deficiency: clinical and genetic study in a large pedigree. Molec. Genet. Metab. 77: 326-331, 2002. 2. Bianchi, M. C., Tosetti, M., Fornai, F., Alessandri, M. G., Cipriani, P., De Vito, G., Canapicchi, R. Reversible brain creatine deficiency in two sisters with normal blood creatine level. Ann. Neurol. 47: 511-513, 2000. 3. Choe, C., Nabuurs, C., Stockebrand, M. C., Neu, A., Nunes, P., Morellini, F., Sauter, K., Schillemeit, S., Hermans-Borgmeyer, I., Marescau, B., Heerschap, A., Isbrandt, D. L-arginine:glycine amidinotransferase deficiency protects from metabolic syndrome. Hum. Molec. Genet. 22: 110-123, 2013. Note: Erratum: Hum. Molec. Genet.: 22: 4030 only, 2013. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))
-
别名
- GATM
-
背景
-
Synonyms: GATM, AGAT, Glycine amidinotransferase, mitochondrial, EC 2.1.4.1, L-arginine:glycine amidinotransferase, Transamidinase
Background: Glycine amidinotransferase, mitochondrial is an enzyme that in humans is encoded by the GATM gene. This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by cognitive disability, language impairment, and behavioral disorders.
-
分子量
- 48 kDa
-
基因ID
- 2628
-
UniProt
- P50440
抗原
-
