MIOX 抗体 (AA 1-266)
Quick Overview for MIOX 抗体 (AA 1-266) (ABIN7599187)
抗原
See all MIOX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-266
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原理
- Anti-MIOX Antibody Picoband®
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产品特性
- Anti-MIOX Antibody Picoband® (ABIN7599187). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MIOX recombinant protein (Position: M1-K266). Human MIOX shares 89.8% and 90.5% amino acid (aa) sequence identity with mouse and rat MIOX, respectively.
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anti-Myo-Inositol Oxygenase (MIOX) (AA 1-285) antibody
MIOX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myo-Inositol Oxygenase (MIOX) (AA 1-285) antibodyMIOX 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Myo-Inositol Oxygenase (MIOX) antibodyMIOX 适用: 人 WB, IF, IHC 宿主: 小鼠 Monoclonal 5H10 unconjugated
anti-Myo-Inositol Oxygenase (MIOX) (AA 1-30), (N-Term) antibodyMIOX 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33052 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry, 2-5 μg/mL, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Arner, R. J., Prabhu, K. S., Thompson, J. T., Hildenbrandt, G. R., Liken, A. D., Reddy, C. C. Myo-inositol oxygenase: molecular cloning and expression of a unique enzyme that oxidizes myo-inositol and D-chiro-inositol. Biochem. J. 360: 313-320, 2001. 2. Gross, M. B. Personal Communication. Baltimore, Md. 3/31/2016. 3. Yang, Q., Dixit, J. B., Wada, J., Tian, Y., Wallner, E. I., Srivastva, S. K., Kanwar, Y. S. Identification of a renal specific oxido-reductase in newborn diabetic mice. Proc. Nat. Acad. Sci. 97: 9896-9901, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MIOX (Myo-Inositol Oxygenase (MIOX))
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别名
- MIOX
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背景
- Myo-inositol oxygenase (MIOX), also known as ALDRL6, is a renal-specific member of the Aldo-keto reductase family. It catalyzes the first committed step in the Myo-inositol metabolism pathway and is widely distributed in mammalian tissues. Human Myo-inositol oxygenase shares 91 % and 96 % sequence homology with mouse and pig Myo-inositol oxygenase homologs, respectively. Myo-inositol oxygenase is responsible for the oxidative cleavage of Myo-inositol (MI) and its epimer D-chiro inositol (DCI) to D-glucuronate. The dioxygen-dependent cleavage of the C1-C6 bond in Myo-inositol is accomplished through the utilization of the FeII/FeIII binuclear iron center of MIOX. Myo-inositol oxygenase has also been implicated in complications of diabetes, including diabetic nephropathy.
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分子量
- 36 kDa
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基因ID
- 55586
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途径
- Inositol Metabolic Process
抗原
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