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ALAS1 抗体 (AA 1-244)

This anti-ALAS1 antibody is a 兔 多克隆 antibody detecting ALAS1 in WB, ELISA 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599146
发货至: 中国

Quick Overview for ALAS1 抗体 (AA 1-244) (ABIN7599146)

抗原

See all ALAS1 抗体
ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ALAS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-244

    原理

    Anti-Alas1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Alas1 Antibody Picoband® (ABIN7599146). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Alas1 recombinant protein (Position: M1-Q244).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Astrin, K. H., Bishop, D. F. Assignment of human erythroid delta-aminolevulinate synthase (ALAS2) to the X chromosome. (Abstract) Cytogenet. Cell Genet. 51: 953-954, 1989. 2. Bawden, M. J., Borthwick, I. A., Healy, H. M., Morris, C. P., May, B. K., Elliott, W. H. Sequence of human 5-aminolevulinate synthase cDNA. Nucleic Acids Res. 15: 8563 only, 1987. 3. Bishop, D. F., Henderson, A. S., Astrin, K. H. Human delta-aminolevulinate synthase: assignment of the housekeeping gene to 3p21 and the erythroid-specific gene to the X chromosome. Genomics 7: 207-214, 1990.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

    别名

    ALAS1

    背景

    Synonyms: Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA

    Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

    Background: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    71 kDa

    基因ID

    211

    UniProt

    P13196

    途径

    Regulation of Lipid Metabolism by PPARalpha
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