THEM4 抗体 (AA 1-240)
Quick Overview for THEM4 抗体 (AA 1-240) (ABIN7599140)
抗原
See all THEM4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-240
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原理
- Anti-THEM4 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-THEM4 Antibody Picoband® (ABIN7599140). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human THEM4 recombinant protein (Position: M1-T240).
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亚型
- IgG
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anti-Thioesterase Superfamily Member 4 (THEM4) (AA 1-240) antibody
THEM4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Thioesterase Superfamily Member 4 (THEM4) (AA 37-150) antibodyTHEM4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioesterase Superfamily Member 4 (THEM4) (Center) antibodyTHEM4 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Maira, S.-M., Galetic, I., Brazil, D. P., Kaech, S., Ingley, E., Thelen, M., Hemmings, B. A. Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane. Science 294: 374-380, 2001. 2. Zhuravleva, E., Gut, H., Hynx, D., Marcellin, D., Bleck, C. K. E., Genoud, C., Cron, P., Keusch, J. J., Dummler, B., Esposti, M. D., Hemmings, B. A. Acyl coenzyme A thioesterase Them5/Acot15 is involved in cardiolipin remodeling and fatty liver development. Molec. Cell. Biol. 32: 2685-2697, 2012. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- THEM4 (Thioesterase Superfamily Member 4 (THEM4))
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别名
- THEM4
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背景
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Synonyms: Protein SOX-15, Protein SOX-12, Protein SOX-20, SOX15, SOX12, SOX20, SOX26, SOX27
Tissue Specificity: Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.
Background: Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas.
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分子量
- 22 kDa
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基因ID
- 117145
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UniProt
- Q5T1C6
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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