GAMT 抗体 (AA 1-236)
Quick Overview for GAMT 抗体 (AA 1-236) (ABIN7599133)
抗原
See all GAMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-236
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原理
- Anti-GAMT Antibody Picoband®
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产品特性
- Anti-GAMT Antibody Picoband® (ABIN7599133). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GAMT recombinant protein (Position: M1-G236). Human GAMT shares 88.1% and 86.8% amino acid (aa) sequence identity with mouse and rat GAMT.
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anti-Guanidinoacetate N-Methyltransferase (GAMT) (AA 64-236) antibody
GAMT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Guanidinoacetate N-Methyltransferase (GAMT) (AA 2-236) antibodyGAMT 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236) antibodyGAMT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanidinoacetate N-Methyltransferase (GAMT) (AA 2-236) antibodyGAMT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236) antibodyGAMT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Guanidinoacetate N-Methyltransferase (GAMT) (AA 101-200) antibodyGAMT 适用: 人 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236) antibodyGAMT 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Guanidinoacetate N-Methyltransferase (GAMT) (N-Term) antibodyGAMT 适用: 人, 大鼠, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Guanidinoacetate N-Methyltransferase (GAMT) antibodyGAMT 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Guanidinoacetate N-Methyltransferase (GAMT) (AA 138-235) antibodyGAMT 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3H4 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Almeida, L. S., Vilarinho, L., Darmin, P. S., Rosenberg, E. H., Martinez-Munoz, C., Jakobs, C., Salomons, G. S. A prevalent pathogenic GAMT mutation (c.59G-C) in Portugal. Molec. Genet. Metab. 91: 1-6, 2007. 2. Caldeira Araujo, H., Smit, W., Verhoeven, N. M., Salomons, G. S., Silva, S., Vasconcelos, R., Tomas, H., Tavares de Almeida, I., Jakobs, C., Duran, M. Guanidinoacetate methyltransferase deficiency identified in adults and a child with mental retardation. Am. J. Med. Genet. 133A: 122-127, 2005. 3. Chae, Y.-J., Chung, C.-E., Kim, B.-J., Lee, M.-H., Lee, H. The gene encoding guanidinoacetate methyltransferase (GAMT) maps to human chromosome 19 at band p13.3 and to mouse chromosome 10. Genomics 49: 162-164, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
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别名
- GAMT
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背景
- Guanidinoacetate N-methyltransferase (EC 2.1.1.2) is an enzyme that catalyzes the chemical reaction and is encoded by gene GAMT located on chromosome 19p13.3. The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.
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分子量
- 26 kDa
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基因ID
- 2593
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UniProt
- Q14353
抗原
-
