RGS18 抗体 (AA 1-230)
Quick Overview for RGS18 抗体 (AA 1-230) (ABIN7599123)
抗原
See all RGS18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-230
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原理
- Anti-RGS18 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RGS18 Antibody Picoband® (ABIN7599123). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RGS18 recombinant protein (Position: M1-D230).
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亚型
- IgG
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anti-Regulator of G-Protein Signalling 18 (RGS18) (C-Term) antibody
Verified RGS18 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 28-84) antibodyRGS18 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 1-235) antibodyRGS18 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (N-Term) antibodyRGS18 适用: 人, 大鼠, 犬, Cow, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 41-90) antibodyRGS18 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 120-169) antibodyRGS18 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Park, I.-K., Klug, C. A., Li, K., Jerabek, L., Li, L., Nanamori, M., Neubig, R. R., Hood, L., Weissman, I. L., Clarke, M. F. Molecular cloning and characterization of a novel regulator of G-protein signaling from mouse hematopoietic stem cells. J. Biol. Chem. 276: 915-923, 2001. 2. Sierra, D. A., Gilbert, D. J., Householder, D., Grishin, N. V., Yu, K., Ukidwe, P., Barker, S. A., He, W., Wensel, T. G., Otero, G., Brown, G., Copeland, N. G., Jenkins, N. A., Wilkie, T. M. Evolution of the regulators of G-protein signaling multigene family in mouse and human. Genomics 79: 177-185, 2002. 3. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
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别名
- RGS18
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背景
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Synonyms: RNA-binding protein Nova-2, Astrocytic NOVA1-like RNA-binding protein, Neuro-oncological ventral antigen 2, NOVA2, ANOVA, NOVA3
Tissue Specificity: Brain. Expression restricted to astrocytes.
Background: Regulator of G-protein signaling 18 is a protein that in humans is encoded by the RGS18 gene. This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
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分子量
- 27 kDa
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基因ID
- 64407
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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