Phospholamban 抗体 (AA 1-23)
Quick Overview for Phospholamban 抗体 (AA 1-23) (ABIN7599122)
抗原
See all Phospholamban (PLN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-23
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原理
- Anti-PLN Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-PLN Antibody Picoband® (ABIN7599122). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PLN recombinant protein (Position: M1-Q23).
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亚型
- IgG
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anti-Phospholamban (PLN) (AA 1-52) antibody
PLN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-30) antibodyPLN 适用: 人 ELISA, WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (pSer16) antibodyPLN 适用: 人 ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (N-Term) antibodyVerified PLN 适用: 人, 大鼠 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Phospholamban (PLN) (Thr17) antibodyPLN 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-35) antibodyPLN 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-52) antibodyPLN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) antibodyPLN 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (pThr17) antibodyPLN 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-30) antibodyPLN 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Rodriguez P, Kranias EG (December 2005). "Phospholamban: a key determinant of cardiac function and dysfunction". Arch Mal Coeur Vaiss 98 (12): 1239-43. 2. McTiernan, C. F., Frye, C. S., Lemster, B. H., Kinder, E. A., Ogletree-Hughes, M. L., Moravec, C. S., Feldman, A. M. : The human phospholamban gene: structure and expression. J. Molec. Cell Cardiol. 31: 679-692, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Phospholamban (PLN)
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别名
- PLN
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背景
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Synonyms: Allograft inflammatory factor 1,AIF-1,Ionized calcium-binding adapter molecule 1,Protein G1,AIF1,G1, IBA1,
Tissue Specificity: Detected in T-lymphocytes and peripheral blood mononuclear cells. .
Background: Phospholamban is a 52 amino acid integral membrane protein that regulates the Ca2+ pump in cardiac muscle and skeletal muscle cells. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. Phospholamban is also expressed in slow-twitch skeletal muscle and some smooth muscle cells. It is observed that human ventricle and quadriceps displayed high levels of phospholamban transcripts and proteins, with markedly lower expression observed in smooth muscles, while the right atrium also expressed low levels of phospholamban. The structure of the human phospholamban gene closely resembles that reported for chicken, rabbit, rat, and mouse. Comparison of the human to other mammalian phospholamban genes indicated a marked conservation of sequence for at least 217 bp upstream of the transcription start site.
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分子量
- 10kDa, 22 kDa
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基因ID
- 5350
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UniProt
- P26678
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途径
- Negative Regulation of Transporter Activity
抗原
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