PREP 抗体 (AA 1-227)
Quick Overview for PREP 抗体 (AA 1-227) (ABIN7599118)
抗原
See all PREP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-227
-
原理
- Anti-Prolyl Endopeptidase/PREP Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Prolyl Endopeptidase/PREP Antibody Picoband® (ABIN7599118). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human PREP recombinant protein (Position: M1-E227).
-
亚型
- IgG
-
-
anti-Prolyl Endopeptidase (PREP) (AA 539-691) antibody
PREP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Prolyl Endopeptidase (PREP) (N-Term) antibodyPREP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prolyl Endopeptidase (PREP) (AA 611-710) antibodyPREP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Prolyl Endopeptidase (PREP) (N-Term) antibodyPREP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Prolyl Endopeptidase (PREP) (C-Term) antibodyPREP 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, Pig, Bat, 小鸡, Drosophila melanogaster, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prolyl Endopeptidase (PREP) (AA 1-710) antibodyPREP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Prolyl Endopeptidase (PREP) (AA 179-228) antibodyPREP 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fulop, V., Bocskei, Z., Polgar, L. Prolyl oligopeptidase: an unusual beta-propeller domain regulates proteolysis. Cell 94: 161-170, 1998. 2. Goossens, F. J., Wauters, J. G., Vanhoof, G. C., Bossuyt, P. J., Schatteman, K. A., Loens, K., Scharpe, S. L. Subregional mapping of the human lymphocyte prolyl oligopeptidase gene (PREP) to human chromosome 6q22. Cytogenet. Cell Genet. 74: 99-101, 1996. 3. Valdivia, A., Irazusta, J., Fernandez, D., Mugica, J., Ochoa, C., Casis, L. Pyroglutamyl peptidase I and prolyl endopeptidase in human semen: increased activity in necrozoospermia. Regulatory Peptides 122: 79-84, 2004. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- PREP (Prolyl Endopeptidase (PREP))
-
别名
- PREP
-
背景
-
Synonyms: Receptor tyrosine-protein kinase erbB-4, Proto-oncogene-like protein c-ErbB-4, Tyrosine kinase-type cell surface receptor HER4, p180erbB4, ERBB4 intracellular domain, 4ICD, E4ICD, s80HER4, ERBB4, HER4
Tissue Specificity: Expressed at highest levels in brain, heart, kidney, in addition to skeletal muscle, parathyroid, cerebellum, pituitary, spleen, testis and breast. Lower levels in thymus, lung, salivary gland, and pancreas. Isoform JM-A CYT-1 and isoform JM-B CYT-1 are expressed in cerebellum, but only the isoform JM-B is expressed in the heart.
Background: Prolyl endopeptidase (PE) also known as prolyl oligopeptidase or post-proline cleaving enzyme is an enzyme that in humans is encoded by the PREP gene. The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides.
-
分子量
- 81 kDa
-
基因ID
- 5550
-
UniProt
- P48147
抗原
-
