PCMT1 抗体 (AA 1-227)
Quick Overview for PCMT1 抗体 (AA 1-227) (ABIN7599116)
抗原
See all PCMT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-227
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原理
- Anti-PCMT1 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-PCMT1 Antibody Picoband® (ABIN7599116). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PCMT1 recombinant protein (Position: M1-K227). Human PCMT1 shares 96% and 95.6% amino acid (aa) sequence identity with mouse and rat PCMT1, respectively.
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亚型
- IgG
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anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 117-225) antibody
PCMT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 62-286) antibodyPCMT1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 117-228) antibodyPCMT1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) antibodyPCMT1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 1-228) antibodyPCMT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G9 unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (Internal Region) antibodyPCMT1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 165-227) antibodyPCMT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 18-55) antibodyPCMT1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal RB56325 unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 93-126) antibodyPCMT1 适用: 人 WB 宿主: 兔 Polyclonal RB56324 unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 209-258) antibodyPCMT1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. DeVry, C. G., Clarke, S. Assignment of the protein L-isoaspartate (D-aspartate) O-methyltransferase gene (PCMT1) to human chromosome bands 6q24-q25 with radiation hybrid mapping. Cytogenet. Cell Genet. 84: 130-131, 1999. 2. Farrar, C., Clarke, S. Altered levels of S-adenosylmethionine and S-adenosylhomocysteine in the brains of L-isoaspartyl (D-aspartyl) O-methyltransferase-deficient mice. J. Biol. Chem. 277: 27856-27863, 2002. 3. Gross, M. B. Personal Communication. Baltimore, Md. 10/13/2022. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
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别名
- PCMT1
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Protein-L-isoaspartate(D-aspartate) O-methyltransferase is an enzyme that in humans is encoded by the PCMT1 gene. This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 25 kDa
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基因ID
- 5110
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UniProt
- P22061
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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