RIOK1 抗体 (AA 1-222)
Quick Overview for RIOK1 抗体 (AA 1-222) (ABIN7599108)
抗原
See all RIOK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-222
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原理
- Anti-RIOK1/RIO1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RIOK1/RIO1 Antibody Picoband® (ABIN7599108). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RIOK1/RIO1 recombinant protein (Position: M1-K222).
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亚型
- IgG
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anti-RIO Kinase 1 (RIOK1) (C-Term) antibody
RIOK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RIO Kinase 1 (RIOK1) (AA 1-568) antibodyRIOK1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-RIO Kinase 1 (RIOK1) (AA 126-156), (N-Term) antibodyRIOK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB9799 unconjugated
anti-RIO Kinase 1 (RIOK1) antibodyRIOK1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RIO Kinase 1 (RIOK1) (AA 1-568) antibodyRIOK1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-RIO Kinase 1 (RIOK1) (AA 233-282) antibodyRIOK1 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-RIO Kinase 1 (RIOK1) (AA 180-479) antibodyRIOK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ameismeier, M., Cheng, J., Berninghausen, O., Beckmann, R. Visualizing late states of human 40S ribosomal subunit maturation. Nature 558: 249-253, 2018. 2. Guderian, G., Peter, C., Wiesner, J., Sickmann, A., Schulze-Osthoff, K., Fischer, U., Grimmler, M. RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity. J. Biol. Chem. 286: 1976-1986, 2011 3. Hartz, P. A. Personal Communication. Baltimore, Md. 10/31/2017. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RIOK1 (RIO Kinase 1 (RIOK1))
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别名
- RIOK1
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背景
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Synonyms: RNA-binding protein Nova-2, Astrocytic NOVA1-like RNA-binding protein, Neuro-oncological ventral antigen 2, NOVA2, ANOVA, NOVA3
Tissue Specificity: Brain. Expression restricted to astrocytes.
Background: Serine/threonine-protein kinase RIO1 is an enzyme that in humans is encode by the RIOK1 gene. The protein encoded by this gene competes with pICln for inclusion in the protein arginine methyltransferase 5 complex. This complex targets substrates for dimethylation. The encoded protein is essential for the last steps in the maturation of 40S subunits.
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分子量
- 66 kDa
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基因ID
- 83732
抗原
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