Tppp 抗体 (AA 1-219)
Quick Overview for Tppp 抗体 (AA 1-219) (ABIN7599102)
抗原
See all Tppp 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-219
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原理
- Anti-TPPP Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-TPPP Antibody Picoband® (ABIN7599102). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TPPP recombinant protein (Position: M1-K219).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Martin, C. P., Vazquez, J., Avila, J., Moreno, F. J. P24, a glycogen synthase kinase 3 (GSK 3) inhibitor. Biochim. Biophys. Acta 1586: 113-122, 2002. 2. Seki, N., Hattori, A., Sugano, S., Suzuki, Y., Nakagawara, A., Muramatsu, M., Hori, T., Saito, T. A novel human gene whose product shares significant homology with the bovine brain-specific protein p25 on chromosome 5p15.3. J. Hum. Genet. 44: 121-122, 1999. 3. Tirian, L., Hlavanda, E., Olah, J., Horvath, I., Orosz, F., Szabo, B., Kovacs, J., Szabad, J., Ovadi, J. TPPP/p25 promotes tubulin assemblies and blocks mitotic spindle formation. Proc. Nat. Acad. Sci. 100: 13976-13981, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Tppp (Tubulin Polymerization Promoting Protein (Tppp))
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别名
- TPPP
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背景
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Synonyms: "Long-chain-fatty-acid--CoA ligase 4, Long-chain acyl-CoA synthetase 4, LACS 4, ACSL4, ACS4, FACL4, LACS4 "
Tissue Specificity: Expressed in the prostate gland and prostate cancers.
Background: Tubulin polymerization-promoting protein is a protein that in humans is encoded by the TPPP gene. Enables several functions, including GTPase activity, magnesium ion binding activity, and protein homodimerization activity. Involved in several processes, including microtubule cytoskeleton organization, negative regulation of tubulin deacetylation, and positive regulation of protein polymerization. Located in several cellular components, including mitochondrion, mitotic spindle, and perinuclear region of cytoplasm. Colocalizes with microtubule and microtubule bundle.
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分子量
- 24 kDa
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基因ID
- 11076
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UniProt
- O94811
抗原
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