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SPAG7 抗体 (AA 1-199)

SPAG7 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7599072
发货至: 中国
  • 抗原 See all SPAG7 抗体
    SPAG7 (Sperm Associated Antigen 7 (SPAG7))
    抗原表位
    AA 1-199
    适用
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 3
    克隆类型
    • 3
    多克隆
    标记
    • 3
    This SPAG7 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
    原理
    Anti-SPAG7 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-SPAG7 Antibody Picoband® (ABIN7599072). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human SPAG7 recombinant protein (Position: M1-D199).
    亚型
    IgG
    Top Product
    Discover our top product SPAG7 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Mao, M., Fu, G., Wu, J.-S., Zhang, Q.-H., Zhou, J., Kan, L.-X., Huang, Q.-H., He, K.-L., Gu, B.-W., Han, Z.-G., Shen, Y., Gu, J., Yu, Y.-P., Xu, S.-H., Wang, Y.-X., Chen, S.-J., Chen, Z. Identification of genes expressed in human CD34+ hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning. Proc. Nat. Acad. Sci. 95: 8175-8180, 1998.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    SPAG7 (Sperm Associated Antigen 7 (SPAG7))
    别名
    SPAG7 (SPAG7 产品)
    背景

    Synonyms: Interactor of HORMAD1 protein 1, Cancer/testis antigen 74, CT74, Coiled-coil domain-containing protein 36, CCDC36, IHO1

    Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

    Background: Sperm-associated antigen 7 is a protein that in humans is encoded by the SPAG7 gene. SPAG7 (sperm-associated antigen 7) is a 227 amino acid nuclear protein that contains one R3H domain and is expressed in fetal brain. The gene that encodes SPAG7 consists of approximately 8,612 bases and maps to human chromosome 17p13.2. Encoding more than 1,200 genes, chromosome 17 comprises over 2.5 % of the human genome. 2 key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is ly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of ovary, colon, prostate gland and fallopian tubes.

    分子量
    35 kDa
    基因ID
    9552
    UniProt
    O75391
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