HSPB8 抗体 (AA 1-196)
Quick Overview for HSPB8 抗体 (AA 1-196) (ABIN7599067)
抗原
See all HSPB8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-196
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原理
- Anti-HSPB8/Hsp22 Antibody Picoband® (monoclonal, 7D8)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HSPB8/Hsp22 Antibody Picoband® (monoclonal, 7D8) (ABIN7599067). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HSPB8/Hsp22 recombinant protein (Position: M1-T196). Human HSPB8/Hsp22 shares 94.4% and 95.4% amino acid (aa) sequence identity with mouse and rat HSPB8/Hsp22, respectively.
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亚型
- IgG2b
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anti-Heat Shock 22kDa Protein 8 (HSPB8) (AA 1-196) antibody
HSPB8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibodyHSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 22kDa Protein 8 (HSPB8) (AA 97-196) antibodyHSPB8 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5B12 unconjugated
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (HRP)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal HRP
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (FITC)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal FITC
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (Biotin)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal Biotin
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (PE)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal PE
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (APC)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal APC
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (PerCP)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal PerCP
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (Atto 488)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal Atto 488
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Smith CC, Yu YX, Kulka M, Aurelian L (Sep 2000). "A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells". J Biol Chem. 275 (33): 25690-9. 2. "Entrez Gene: HSPB8 Heat shock 22 kDa protein 8". -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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别名
- HSPB8
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背景
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Synonyms: CMT2L, CRYAC, DHMN 2, DHMN2, E2IG1, H11, HMN 2, HMN2, HMN2A, HSB8, HSPB 8, HspB8
Tissue Specificity: Predominantly expressed in skeletal muscle and heart.
Background: Heat shock protein beta-8 is a protein that in humans is encoded by the HSPB8 gene. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
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分子量
- 22 kDa
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基因ID
- 26353
抗原
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