CBX5 抗体 (AA 1-191)
Quick Overview for CBX5 抗体 (AA 1-191) (ABIN7599057)
抗原
See all CBX5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-191
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原理
- Anti-HP1 alpha/CBX5 Antibody Picoband® (monoclonal, 8G6)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HP1 alpha/CBX5 Antibody Picoband® (monoclonal, 8G6) (ABIN7599057). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HP1 alpha/CBX5 recombinant protein (Position: M1-S191).
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亚型
- IgG2b
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anti-Chromobox Homolog 5 (CBX5) (Internal Region) antibody
Verified CBX5 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) antibodyCBX5 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1B10B2 unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人, 小鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3A11F8 unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E11-3A10 unconjugated
anti-Chromobox Homolog 5 (CBX5) antibodyCBX5 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) (AA 1-191) antibodyCBX5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 5 (CBX5) antibodyCBX5 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 7B6 unconjugated
anti-Chromobox Homolog 5 (CBX5) antibodyCBX5 适用: 人, 小鼠 WB, IHC, ICC 宿主: 小鼠 Monoclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Allan, R. S., Zueva, E., Cammas, F., Schreiber, H. A., Masson, V., Belz, G. T., Roche, D., Maison, C., Quivy, J.-P., Almouzni, G., Amigorena, S. An epigenetic silencing pathway controlling T helper 2 cell lineage commitment. Nature 487: 249-253, 2012. 2. Bannister, A. J., Zegerman, P., Partridge, J. F., Miska, E. A., Thomas, J. O., Allshire, R. C., Kouzarides, T. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410: 120-124, 2001. 3. Cheutin, T., McNairn, A. J., Jenuwein, T., Gilbert, D. M., Singh, P. B., Misteli, T. Maintenance of stable heterochromatin domains by dynamic HP1 binding. Science 299: 721-725, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CBX5 (Chromobox Homolog 5 (CBX5))
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别名
- CBX5
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背景
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Synonyms: N-myc-interactor, Nmi, N-myc and STAT interactor, NMI
Tissue Specificity: Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver.
Background: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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分子量
- 22 kDa
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基因ID
- 23468
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UniProt
- P45973
抗原
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