ALAS2 抗体 (AA 1-190)
Quick Overview for ALAS2 抗体 (AA 1-190) (ABIN7599056)
抗原
See all ALAS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-190
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原理
- Anti-ALAS2/ASB Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ALAS2/ASB Antibody Picoband® (ABIN7599056). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ALAS2/ASB recombinant protein (Position: M1-D190).
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亚型
- IgG
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anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 1-100) antibody
ALAS2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C1 unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (Center) antibodyALAS2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 50-320) antibodyALAS2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 50-587) antibodyALAS2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 164-213) antibodyALAS2 适用: 人, 大鼠, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) antibodyALAS2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 470-519) antibodyALAS2 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, Pig, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 38-87) antibodyALAS2 适用: 人, 小鼠, Cow, 兔, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (AA 398-447) antibodyALAS2 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 2 (ALAS2) (C-Term) antibodyALAS2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Aoki, Y., Urata, G., Takaku, F. Delta-aminolevulinic acid synthetase activity in erythroblasts of patients with primary sideroblastic anemia. Acta Haemat. Jpn. 36: 74-77, 1973. 2. Astner, I., Schulze, J. O., van den Heuvel, J., Jahn, D., Schubert, W.-D., Heinz, D. W. Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans. EMBO J. 24: 3166-3177, 2005. 3. Astrin, K. H., Bishop, D. F. Assignment of human erythroid delta-aminolevulinate synthase (ALAS2) to the X chromosome. (Abstract) Cytogenet. Cell Genet. 51: 953-954, 1989. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))
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别名
- ALAS2
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背景
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Synonyms: Endothelin-converting enzyme 1,ECE-1,3.4.24.71,ECE1,
Tissue Specificity: All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma, isoforms A and C in liver, testis and small intestine, isoform B, C and D in endothelial cells and umbilical vein smooth muscle cells, isoforms C and D in saphenous vein cells, and isoform C in kidney. .
Background: Delta-aminolevulinate synthase 2 also known as ALAS2 is a protein that in humans is encoded by the ALAS2 gene. The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
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分子量
- 65 kDa
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基因ID
- 212
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UniProt
- P22557
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途径
- Transition Metal Ion Homeostasis
抗原
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