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PPIH 抗体 (AA 1-177)

This anti-PPIH antibody is a 兔 多克隆 antibody detecting PPIH in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599038
发货至: 中国

Quick Overview for PPIH 抗体 (AA 1-177) (ABIN7599038)

抗原

See all PPIH 抗体
PPIH (Peptidylprolyl Isomerase H (Cyclophilin H) (PPIH))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PPIH antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 1-177

    原理

    Anti-PPIH Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-PPIH Antibody Picoband® (ABIN7599038). Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PPIH recombinant protein (Position: M1-M177). Human PPIH shares 100% amino acid (aa) sequence identity with mouse PPIH.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL
    1. Horowitz, D. S., Kobayashi, R., Krainer, A. R. A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs. RNA 3: 1374-1387, 1997. 2. Reidt, U., Reuter, K., Achsel, T., Ingelfinger, D., Luhrmann, R., Ficner, R. Crystal structure of the human U4/U6 small nuclear ribonucleoprotein particle-specific SnuCyp-20, a nuclear cyclophilin. J. Biol. Chem. 275: 7439-7442, 2000. 3. Teigelkamp, S., Achsel, T., Mundt, C., Gothel, S.-F., Cronshagen, U., Lane, W. S., Marahiel, M., Luhrmann, R. The 20kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD proteins. RNA 4: 127-141, 1998.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    PPIH (Peptidylprolyl Isomerase H (Cyclophilin H) (PPIH))

    别名

    PPIH

    背景

    Synonyms: PPIH, CYP20, CYPH, Peptidyl-prolyl cis-trans isomerase H, PPIase H, EC 5.2.1.8, Rotamase H, Small nuclear ribonucleoprotein particle-specific cyclophilin H, Cy pH , U-snRNP-associated cyclophilin SnuCyp-20, USA-CYP

    Background: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.

    分子量

    19 kDa

    基因ID

    10465

    UniProt

    O43447
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