NLRP7 抗体 (AA 1-169)
Quick Overview for NLRP7 抗体 (AA 1-169) (ABIN7599027)
抗原
See all NLRP7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-169
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原理
- Anti-NLRP7 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NLRP7 Antibody Picoband® (ABIN7599027). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NLRP7 recombinant protein (Position: M1-L169).
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亚型
- IgG
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anti-NLR Family, Pyrin Domain Containing 7 (NLRP7) (AA 89-187) antibody
NLRP7 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Agarwal, P., Bagga, R., Jain, V., Kalra, J., Gopalan, S. Familial recurrent molar pregnancy: a case report. Acta Obstet. Gynecol. Scand. 83: 213-214, 2004. 2. Aghajanova, L., Mahadevan, S., Altmae, S., Stravreus-Evers, A., Regan, L., Sebire, N., Dixon, P., Fisher, R. A., Van den Veyver, I. B. No evidence for mutations in NLRP7, NLRP2 or KHDC3L in women with unexplained recurrent pregnancy loss or infertility. Hum. Reprod. 30: 232-238, 2015. 3. Andreasen, L., Bolund, L., Niemann, I., Hansen, E. S., Sunde, L. Mosaic moles and non-familial biparental moles are not caused by mutation in NLRP7, NLRP2 or C6orf221. Molec. Hum. Reprod. 18: 593-598, 2012. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))
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别名
- NLRP7
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背景
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Synonyms: Protein SOX-15, Protein SOX-12, Protein SOX-20, SOX15, SOX12, SOX20, SOX26, SOX27
Tissue Specificity: Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.
Background: NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene. This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 112 kDa
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基因ID
- 199713
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途径
- Inflammasome
抗原
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