C4orf49 抗体 (AA 1-155)
This anti-C4orf49 antibody is a 兔 多克隆 antibody detecting C4orf49 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for C4orf49 抗体 (AA 1-155) (ABIN7599013)
抗原
See all C4orf49 抗体
C4orf49
(Chromosome 4 Open Reading Frame 49 (C4orf49))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This C4orf49 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
-
-
抗原表位
- AA 1-155
-
原理
- Anti-MGARP Antibody Picoband®
-
产品特性
- Anti-MGARP Antibody Picoband® (ABIN7599013). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human C4orf49/MGARP recombinant protein (Position: M1-E155). Human C4orf49/MGARP shares 67.3% amino acid (aa) sequence identity with mouse C4orf49/MGARP.
-
-
anti-Chromosome 4 Open Reading Frame 49 (C4orf49) (AA 176-204), (C-Term) antibody
C4orf49 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Jia, L., Liang, T., Yu, X., Ma, C., Zhang, S. MGARP regulates mouse neocortical development via mitochondrial positioning. Molec. Neurobiol. 49: 1293-1308, 2014. 2. Matsumoto, T., Minegishi, K., Ishimoto, H., Tanaka, M., Hennebold, J. D., Teranishi, T., Hattori, Y., Furuya, M., Higuchi, T., Asai, S., Kim, S. H., Miyakoshi, K., Yoshimura, Y. Expression of ovary-specific acidic protein in steroidogenic tissues: a possible role in steroidogenesis. Endocrinology 150: 3353-3359, 2009. 3. Qi, S., Wang, Y., Zhou, M., Ge, Y., Yan, Y., Wang, J., Zhang, S. S.-M., Zhang, S. A mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) is highly expressed in retina that exhibits a large area of intrinsic disorder. Molec. Biol. Rep. 38: 2869-2877, 2011. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- C4orf49 (Chromosome 4 Open Reading Frame 49 (C4orf49))
-
别名
- MGARP
-
背景
- MGARP is highly enriched in steroidogenic tissues and the visual system. Interestingly, its expression increases as mice develop. Early in development, MGARP is mainly detected in the retina and adrenal gland. At this early developmental stage, its expression is not detectable in the gonads, but its expression in the gonads dramatically increases during the first 2-4 wk after birth. Importantly, MGARP levels correlate with estrogen levels in the ovaries during the estrous cycle, and estrogen regulates the expression of MGARP in a tissue-specific manner and through a feedback regulatory mechanism. Functional inhibition of GnRH with an antagonist strongly reduces MGARP levels, and knockout of leptin (ob/ob) significantly reduces the MGARP expression in follicular granular cells. We proposed a model that elucidates the role MGARP plays in the HPG axis. Within the HPG axis loop, MGARP participates in hormone biosynthesis while being under the regulation of the hormones derived from the HPG axis.
-
分子量
- 38 kDa
-
基因ID
- 84709
抗原
-
You are here:
