SSBP1 抗体 (AA 1-148)
Quick Overview for SSBP1 抗体 (AA 1-148) (ABIN7599002)
抗原
See all SSBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-148
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原理
- Anti-SSBP1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-SSBP1 Antibody Picoband® (ABIN7599002). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SSBP1 recombinant protein (Position: M1-E148).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bogenhagen, D. F., Rousseau, D., Burke, S. The layered structure of human mitochondrial DNA nucleoids. J. Biol. Chem. 283: 3665-3675, 2008. 2. Del Dotto, V., Ullah, F., Di Meo, I., Magini, P., Gusic, M., Maresca, A., Caporali, L., Palombo, F., Tagliavini, F., Baugh, E. H., Macao, B., Szilagyi, Z., and 35 others. SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder. J. Clin. Invest. 130: 108-125, 2020. 3. Huang, J., Gong, Z., Ghosal, G., Chen, J. SOSS complexes participate in the maintenance of genomic stability. Molec. Cell 35: 384-393, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SSBP1 (Single-Stranded DNA Binding Protein 1 (SSBP1))
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别名
- SSBP1
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背景
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Synonyms: Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25,
Tissue Specificity: Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen .
Background: Single-stranded DNA-binding protein, mitochondrial is a protein that in humans is encoded by the SSBP1 gene. SSBP1 is a housekeeping gene involved in mitochondrial biogenesis. It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability.
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分子量
- 16 kDa
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基因ID
- 6742
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UniProt
- Q04837
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途径
- Chromatin Binding
抗原
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