RPS19 抗体 (AA 1-145)
Quick Overview for RPS19 抗体 (AA 1-145) (ABIN7599000)
抗原
See all RPS19 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-145
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原理
- Anti-RPS19 Antibody Picoband®
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产品特性
- Anti-RPS19 Antibody Picoband® (ABIN7599000). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RPS19 recombinant protein (Position: M1-H145). Human RPS19 shares 99.3% amino acid (aa) sequence identity with both mouse and rat RPS19.
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anti-Ribosomal Protein S19 (RPS19) (Internal Region) antibody
Verified RPS19 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ribosomal Protein S19 (RPS19) (Internal Region) antibodyRPS19 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S19 (RPS19) (AA 1-145) antibodyRPS19 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C6 unconjugated
anti-Ribosomal Protein S19 (RPS19) antibodyRPS19 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Ribosomal Protein S19 (RPS19) (AA 1-145) antibodyRPS19 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S19 (RPS19) antibodyRPS19 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S19 (RPS19) (AA 25-54) antibodyRPS19 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB31945 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Angelini, M., Cannata, S., Mercaldo, V., Gibello, L., Santoro, C., Dianzani, I., Loreni, F. Missense mutations associated with Diamond-Blackfan anemia affect the assembly of ribosomal protein S19 into the ribosome. Hum. Molec. Genet. 16: 1720-1727, 2007. 2. Chatr-aryamontri, A., Angelini, M., Garelli, E., Tchernia, G., Ramenghi, U., Dianzani, I., Loreni, F. Nonsense-mediated and nonstop decay of ribosomal protein S19 mRNA in Diamond-Blackfan anemia. Hum. Mutat. 24: 526-533, 2004. 3. Da Costa, L., Tchernia, G., Gascard, P., Lo, A., Meerpohl, J., Niemeyer, C., Chasis, J.-A., Fixler, J., Mohandas, N. Nucleolar localization of RPS19 protein in normal cells and mislocalization due to mutations in the nucleolar localization signals in 2 Diamond-Blackfan anemia patients: potential insights into pathophysiology. Blood 101: 5039-5045, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RPS19 (Ribosomal Protein S19 (RPS19))
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别名
- RPS19
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背景
- 40S ribosomal protein S19 is a protein that in humans is encoded by the RPS19 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
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分子量
- 16 kDa
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基因ID
- 6223
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UniProt
- P39019
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途径
- Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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