NDUFA13 抗体 (AA 1-144)
Quick Overview for NDUFA13 抗体 (AA 1-144) (ABIN7598998)
抗原
See all NDUFA13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-144
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原理
- Anti-GRIM19/NDUFA13 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GRIM19/NDUFA13 Antibody Picoband® (ABIN7598998). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GRIM19/NDUFA13 recombinant protein (Position: M1-T144).
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亚型
- IgG
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anti-NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13) (AA 1-144) antibody
NDUFA13 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13) (AA 1-144) antibodyNDUFA13 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13) (N-Term) antibodyNDUFA13 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13) (AA 52-144) antibodyNDUFA13 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13) antibodyNDUFA13 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13) (AA 51-144) antibodyNDUFA13 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13) (AA 1-144) antibodyNDUFA13 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Angebault, C., Charif, M., Guegen, N., Piro-Megy, C., Mousson de Camaret, B., Procaccio, V., Guichet, P.-O., Hebrard, M., Manes, G., Leboucq, N., Rivier, F., Hamel, C. P., Lenaers, G., Roubertie, A. Mutation in NDUFA13/GRIM19 leads to early onset hypotonia, dyskinesia and sensorial deficiencies, and mitochondrial complex I instability. Hum. Molec. Genet. 24: 3948-3955, 2015. 2. Angell, J. E., Lindner, D. J., Shapiro, P. S., Hofmann, E. R., Kalvakolanu, D. V. Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach. J. Biol. Chem. 275: 33416-33426, 2000. 3. Barnich, N., Hisamatsu, T., Aguirre, J. E., Xavier, R., Reinecker, H.-C., Podolsky, D. K. GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells. J. Biol. Chem. 280: 19021-19026, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))
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别名
- NDUFA13
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背景
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Synonyms: Long-chain-fatty-acid--CoA ligase 3,6.2.1.3,Long-chain acyl-CoA synthetase 3,LACS 3,ACSL3,ACS3, FACL3, LACS3,
Tissue Specificity: Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck tumors and embryonal tumor.
Background: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 is an enzyme that in humans is encoded by the NDUFA13 gene. This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined.
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分子量
- 16 kDa, 17 kDa
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基因ID
- 51079
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UniProt
- Q9P0J0
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途径
- Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling
抗原
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