SIVA1 抗体 (AA 1-141)
Quick Overview for SIVA1 抗体 (AA 1-141) (ABIN7598994)
抗原
See all SIVA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-141
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原理
- Anti-SIVA/SIVA1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SIVA/SIVA1 Antibody Picoband® (ABIN7598994). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SIVA/SIVA1 recombinant protein (Position: M1-T141).
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亚型
- IgG
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anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-175) antibody
SIVA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-110) antibodySIVA1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (Internal Region) antibodySIVA1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-110) antibodySIVA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-175) antibodySIVA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) antibodySIVA1 适用: 人 WB 宿主: 小鼠 Monoclonal 1G8 unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) antibodySIVA1 适用: 人 WB 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-110) antibodySIVA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (N-Term) antibodySIVA1 适用: 人, 小鼠 WB, IF, EIA 宿主: 小鸡 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Nestler, M., Martin, U., Hortschansky, P., Saluz, H.-P., Henke, A., Munder, T. The zinc containing pro-apoptotic protein siva interacts with the peroxisomal membrane protein pmp22. Molec. Cell. Biochem. 287: 147-155, 2006. 2. Prasad, K. V. S., Ao, Z., Yoon, Y., Wu, M. X., Rizk, M., Jacquot, S., Schlossman, S. F. CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein. Proc. Nat. Acad. Sci. 94: 6346-6351, 1997. 3. Py, B., Slomianny, C., Auberger, P., Petit, P. X., Benichou, S. Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway. J. Immun. 172: 4008-4017, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))
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别名
- SIVA1
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背景
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Synonyms: POU domain, class 4, transcription factor 1
Tissue Specificity: Expressed in the brain and the retina. Present in the developing brain, spinal cord and eye.
Background: Apoptosis regulatory protein Siva is a protein that in humans is encoded by the SIVA1 gene. This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis.
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分子量
- 19 kDa
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基因ID
- 10572
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UniProt
- O15304
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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