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PRDM2 抗体 (AA 1-1378)

This anti-PRDM2 antibody is a 兔 多克隆 antibody detecting PRDM2 in WB, ELISA, IHC, ICC, FACS 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7598989
发货至: 中国

Quick Overview for PRDM2 抗体 (AA 1-1378) (ABIN7598989)

抗原

See all PRDM2 抗体
PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

适用

人, 小鼠, 大鼠

宿主

  • 54
  • 11

克隆类型

  • 55
  • 10
多克隆

标记

  • 16
  • 6
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PRDM2 antibody is un-conjugated

应用范围

  • 35
  • 26
  • 26
  • 24
  • 13
  • 9
  • 8
  • 6
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 15
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-1378

    原理

    Anti-PRDM2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PRDM2 Antibody Picoband® (ABIN7598989). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PRDM2 recombinant protein (Position: M1-Q1378).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Buyse, I. M., Shao, G., Huang, S. The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein. Proc. Nat. Acad. Sci. 92: 4467-4471, 1995. 2. Buyse, I. M., Takahashi, E., Huang, S. Physical mapping of the retinoblastoma interacting zinc finger gene RIZ to D1S228 on chromosome 1p36. Genomics 34: 119-121, 1996. 3. Chadwick, R. B., Jiang, G.-L., Bennington, G. A., Yuan, B., Johnson, C. K., Stevens, M. W., Niemann, T. H., Peltomaki, P., Huang, S., de la Chapelle, A. Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis. Proc. Nat. Acad. Sci. 97: 2662-2667, 2000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

    别名

    PRDM2

    背景

    Synonyms: Thrombopoietin, C-mpl ligand, ML, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand, THPO, MGDF

    Tissue Specificity: Found mainly in the liver, kidney and skeletal muscle.

    Background: PR domain zinc finger protein 2 is a protein that in humans is encoded by the PRDM2 gene. This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    280 kDa

    基因ID

    7799

    UniProt

    Q13029
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