Msx2/Hox8 抗体 (AA 1-129)
Quick Overview for Msx2/Hox8 抗体 (AA 1-129) (ABIN7598976)
抗原
See all Msx2/Hox8 (Msx2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-129
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原理
- Anti-Hox8/MSX2 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Hox8/MSX2 Antibody Picoband® (ABIN7598976). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Hox8/MSX2 recombinant protein (Position: M1-M129).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bernardini, L., Castori, M., Capalbo, A., Mokini, V., Mingarelli, R., Simi, P., Bertuccelli, A., Novelli, A., Dallapiccola, B. Syndromic craniosynostosis due to complex chromosome 5 rearrangement and MSX2 gene triplication. Am. J. Med. Genet. 143A: 2937-2943, 2007. 2. Davidson, D. The function and evolution of Msx genes: pointers and paradoxes. Trends Genet. 11: 405-411, 1995. 3. Florisson, J. M. G., Verkerk, A. J. M. H., Huigh, D., Hoogeboom, A. J. M., Swagemakers, S., Kremer, A., Heijsman, D., Lequin, M. H., Mathijssen, I. M. J., van der Spek, P. J. Boston type craniosynostosis: report of a second mutation in MSX2. Am. J. Med. Genet. 161A: 2626-2633, 2013. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))
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别名
- MSX2
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背景
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Synonyms: Farnesyl pyrophosphate synthase, FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Cholesterol-regulated 39 kDa protein, CR 39, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase, Fdps
Tissue Specificity: Expressed ubiquitously.
Background: Homeobox protein MSX-2 is a protein that in humans is encoded by the MSX2 gene. This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
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分子量
- 37 kDa
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基因ID
- 4488
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UniProt
- P35548
抗原
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