ADAR 抗体 (AA 1-1152)
Quick Overview for ADAR 抗体 (AA 1-1152) (ABIN7598956)
抗原
See all ADAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-1152
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原理
- Anti-ADAR1/ADAR Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ADAR1/ADAR Antibody Picoband® (ABIN7598956). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ADAR1/ADAR recombinant protein (Position: M1-E1152).
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亚型
- IgG
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anti-Adenosine Deaminase, RNA-Specific (ADAR) (AA 1-1226) antibody
ADAR 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific (ADAR) (AA 150-250) antibodyADAR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific (ADAR) antibodyKO Validated ADAR 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific (ADAR) (AA 1085-1223) antibodyADAR 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E2E4 unconjugated
anti-Adenosine Deaminase, RNA-Specific (ADAR) (AA 1-1226) antibodyADAR 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific (ADAR) (AA 1085-1223) antibodyADAR 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4E2B5 unconjugated
anti-Adenosine Deaminase, RNA-Specific (ADAR) (AA 151-250) antibodyADAR 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific (ADAR) (AA 367-471) antibodyADAR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific (ADAR) (N-Term) antibodyADAR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific (ADAR) (C-Term) antibodyADAR 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Agranat, L., Raitskin, O., Sperling, J., Sperling, R. The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus. Proc. Nat. Acad. Sci. 105: 5028-5033, 2008. 2. Bass, B. L., Weintraub, H. An unwinding activity that covalently modifies its double-stranded RNA substrate. Cell 55: 1089-1098, 1988. 3. Chao, S.-C., Huang, C.-Y., Yang, M.-H. A novel nonsense mutation of the DSRAD gene in a Taiwanese family with dyschromatosis symmetrica hereditaria. Europ. J. Derm. 16: 449-540, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
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别名
- ADAR
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背景
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Synonyms: Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, T-cell antigen 4-1BB, CD137, Tnfrsf9, Cd137, Ila, Ly63
Tissue Specificity: Expressed on the surface of activated T-cells.
Background: Double-stranded RNA-specific adenosine deaminase is an enzyme that in humans is encoded by the ADAR gene. This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
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分子量
- 110 kDa
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基因ID
- 103
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UniProt
- P55265
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途径
- Protein targeting to Nucleus
抗原
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