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TBCA 抗体 (AA 1-108)

This anti-TBCA antibody is a 兔 多克隆 antibody detecting TBCA in WB, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN7598945
发货至: 中国

Quick Overview for TBCA 抗体 (AA 1-108) (ABIN7598945)

抗原

See all TBCA 抗体
TBCA (Tubulin Folding Cofactor A (TBCA))

适用

  • 39
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宿主

  • 43
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克隆类型

  • 43
  • 4
多克隆

标记

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This TBCA antibody is un-conjugated

应用范围

  • 34
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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 9
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    AA 1-108

    原理

    Anti-CFA/TBCA Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-CFA/TBCA Antibody Picoband® (ABIN7598945). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CFA/TBCA recombinant protein (Position: M1-A108).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Mao, M., Fu, G., Wu, J.-S., Zhang, Q.-H., Zhou, J., Kan, L.-X., Huang, Q.-H., He, K.-L., Gu, B.-W., Han, Z.-G., Shen, Y., Gu, J., Yu, Y.-P., Xu, S.-H., Wang, Y.-X., Chen, S.-J., Chen, Z. Identification of genes expressed in human CD34+ hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning. Proc. Nat. Acad. Sci. 95: 8175-8180, 1998. 2. Nolasco, S., Bellido, J., Goncalves, J., Zabala, J. C., Soares, H. Tubulin cofactor A gene silencing in mammalian cells induces changes in microtubule cytoskeleton, cell cycle arrest and cell death. FEBS Lett. 579: 3515-3524, 2005. 3. Tian, G., Huang, Y., Rommelaere, H., Vandekerckhove, J., Ampe, C., Cowan, N. J. Pathway leading to correctly folded beta-tubulin. Cell 86: 287-296, 1996.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    TBCA (Tubulin Folding Cofactor A (TBCA))

    别名

    TBCA

    背景

    Synonyms: Interleukin-34, IL-34, IL34, C16orf77

    Tissue Specificity: Detected in the sinusoidal epithelium in the red pulp of spleen. Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.

    Background: Tubulin-specific chaperone A is a protein that in humans is encoded by the TBCA gene. The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex, interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    18 kDa

    基因ID

    6902

    UniProt

    O75347

    途径

    SARS-CoV-2 Protein Interactome
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