Glutaredoxin 1 抗体 (AA 1-106)
Quick Overview for Glutaredoxin 1 抗体 (AA 1-106) (ABIN7598941)
抗原
See all Glutaredoxin 1 (GRX1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-106
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原理
- Anti-Glutaredoxin 1/GLRX Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Glutaredoxin 1/GLRX Antibody Picoband® (ABIN7598941). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Glutaredoxin 1/GLRX recombinant protein (Position: M1-Q106).
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亚型
- IgG
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anti-Glutaredoxin 1 (GRX1) (AA 1-106) antibody
GRX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 1 (GRX1) (AA 2-107) antibodyGRX1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 1 (GRX1) antibodyGRX1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 1 (GRX1) (AA 1-106) antibodyGRX1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Glutaredoxin 1 (GRX1) (AA 1-106) antibodyGRX1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 1 (GRX1) (N-Term) antibodyGRX1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 1 (GRX1) antibodyGRX1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 1 (GRX1) antibodyGRX1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 1 (GRX1) (AA 38-87) antibodyGRX1 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 犬, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 1 (GRX1) (AA 30-79) antibodyGRX1 适用: 人, 小鼠, 大鼠, Cow, 兔, 绵羊, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Padilla, C. A., Bajalica, S., Lagercrantz, J., Holmgren, A. The gene for human glutaredoxin (GLRX) is localized to human chromosome 5q14. Genomics 32: 455-457, 1996. 2. Padilla, C. A., Martinez-Galisteo, E., Barcena, J. A., Spyrou, G., Holmgren, A. Purification from placenta, amino acid sequence, structure comparisons and cDNA cloning of human glutaredoxin. Europ. J. Biochem. 227: 27-34, 1995. 3. Raghavachari, N., Krysan, K., Xing K., Lou, M. F. Regulation of thioltransferase expression in human lens epithelial cells. Invest. Ophthal. Vis. Sci. 42: 1002-1008, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Glutaredoxin 1 (GRX1)
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别名
- GLRX
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背景
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Synonyms: Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, Gc
Background: Glutaredoxin-1 is a protein that in humans is encoded by the GLRX gene. This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
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分子量
- 12 kDa
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基因ID
- 2745
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UniProt
- P35754
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途径
- Cell RedoxHomeostasis
抗原
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