alpha KGDHC 抗体 (AA 1-1023)
Quick Overview for alpha KGDHC 抗体 (AA 1-1023) (ABIN7598935)
抗原
See all alpha KGDHC (alphaKGDHC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-1023
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原理
- Anti-OGDH Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-OGDH Antibody Picoband® (ABIN7598935). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human OGDH recombinant protein (Position: M1-S1023).
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亚型
- IgG
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anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 148-427) antibody
alphaKGDHC 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (C-Term) antibodyalphaKGDHC 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) antibodyalphaKGDHC 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (N-Term) antibodyalphaKGDHC 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 41-423) antibodyalphaKGDHC 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (N-Term) antibodyalphaKGDHC 适用: 人, Cow, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (N-Term) antibodyalphaKGDHC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 256-582) antibodyalphaKGDHC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 381-410), (C-Term) antibodyalphaKGDHC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32469 unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) antibodyalphaKGDHC 适用: 人, 大鼠, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Koike, K., Urata, Y., Goto, S. Cloning and nucleotide sequence of the cDNA encoding human 2-oxoglutarate dehydrogenase (lipoamide). Proc. Nat. Acad. Sci. 89: 1963-1967, 1992. 2. Koike, K. The gene encoding human 2-oxoglutarate dehydrogenase: structural organization and mapping to chromosome 7p13-p14. Gene 159: 261-266, 1995. 3. Liu, Y., You, Y., Lu, Z., Yang, J., Li, P., Liu, L., Xu, H., Niu, Y., Cao, X. N(6)-methyladenosine RNA modification-mediated cellular metabolism rewiring inhibits viral replication. Science 365: 1171-1176, 2019. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
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别名
- OGDH
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背景
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Synonyms: Loricrin, LOR, LRN
Tissue Specificity: Expressed in testis and to a lesser degree in brain, ovary and placenta. Found in most tissues at low levels.
Background: Alpha-ketoglutarate dehydrogenase also known as 2-oxoglutarate dehydrogenase E1 component, mitochondrial is an enzyme that in humans is encoded by the OGDH gene. This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[
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分子量
- 110 kDa
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基因ID
- 4967
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UniProt
- Q02218
抗原
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