FYCO1 抗体 (AA 1-1019)
Quick Overview for FYCO1 抗体 (AA 1-1019) (ABIN7598934)
抗原
See all FYCO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-1019
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原理
- Anti-FYCO1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-FYCO1 Antibody Picoband® (ABIN7598934). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FYCO1 recombinant protein (Position: M1-K1019). Human FYCO1 shares 72.2% amino acid (aa) sequence identity with mouse FYCO1.
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亚型
- IgG
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anti-FYVE and Coiled-Coil Domain Containing 1 (FYCO1) (AA 1-255) antibody
FYCO1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-FYVE and Coiled-Coil Domain Containing 1 (FYCO1) (AA 2-255) antibodyFYCO1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FYVE and Coiled-Coil Domain Containing 1 (FYCO1) (Internal Region) antibodyFYCO1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FYVE and Coiled-Coil Domain Containing 1 (FYCO1) (AA 1051-1150) antibodyFYCO1 适用: 人, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Chen, J., Ma, Z., Jiao, X., Fariss, R., Kantorow, W. L., Kantorow, M., Pras, E., Frydman, M., Pras, E., Riazuddin, S., Riazuddin, S. A., Hejtmancik, J. F. Mutations in FYCO1 cause autosomal-recessive congenital cataracts. Am. J. Hum. Genet. 88: 827-838, 2011. 2. Kiss, H., Yang, Y., Kiss, C., Andersson, K., Klein, G., Imreh, S., Dumanski, J. P. The transcriptional map of the common eliminated region 1 (C3CER1) in 3p21.3. Europ. J. Hum. Genet. 10: 52-61, 2002. 3. Pras, E., Pras, E., Bakhan, T., Levy-Nissenbaum, E., Lahat, H., Assia, E. I., Garzozi, H. J., Kastner, D. L., Goldman, B., Frydman, M. A gene causing autosomal recessive cataract maps to the short arm of chromosome 3. Isr. Med. Assoc. J. 3: 559-562, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- FYCO1 (FYVE and Coiled-Coil Domain Containing 1 (FYCO1))
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别名
- FYCO1
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背景
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Synonyms: FYCO1, ZFYVE7, FYVE and coiled-coil domain-containing protein 1, Zinc finger FYVE domain-containing protein 7
Background: The gene encodes a Rab7 adapter protein that is implicated in the microtubule transport of autophagosomes. The encoded protein contains a RUN domain, a FYVE-type zinc finger domain, and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P), the autophagosome marker LC3, and the kinesin KIF5. Mutations in this gene are associated with inclusion body myositis (IBM) and autosomal recessive congenital cataracts (CATC2).
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分子量
- 167 kDa
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基因ID
- 79443
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途径
- SARS-CoV-2 Protein Interactome
抗原
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