OGDHL 抗体 (AA 1-1010)
Quick Overview for OGDHL 抗体 (AA 1-1010) (ABIN7598933)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-1010
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原理
- Anti-OGDHL Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-OGDHL Antibody Picoband® (ABIN7598933). Tested in ELISA, IF, ICC, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human OGDHL recombinant protein (Position: M1-F1010).
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亚型
- IgG
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anti-Oxoglutarate Dehydrogenase-Like (OGDHL) (AA 1-110) antibody
OGDHL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Oxoglutarate Dehydrogenase-Like (OGDHL) (AA 26-75) antibodyOGDHL 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Oxoglutarate Dehydrogenase-Like (OGDHL) (N-Term) antibodyOGDHL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Oxoglutarate Dehydrogenase-Like (OGDHL) (N-Term) antibodyOGDHL 适用: 人, 大鼠, 犬, Pig, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bunik, V. I., Degtyarev, D. Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins. Proteins 71: 874-890, 2008. 2. Nagase, T., Ishikawa, K., Kikuno, R., Hirosawa, M., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 6: 337-345, 1999. 3. Sen, T., Sen, N., Noordhuis, M. G., Ravi, R., Wu, T.-C., Ha, P. K., Sidransky, D., Hoque, M. O. OGDHL is a modifier of AKT-dependent signaling and NF-kappaB function. PLoS One 7: e48770, 2012. Note: Electronic Article. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- OGDHL (Oxoglutarate Dehydrogenase-Like (OGDHL))
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别名
- OGDHL
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背景
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Synonyms: RNA-binding protein Nova-2, Astrocytic NOVA1-like RNA-binding protein, Neuro-oncological ventral antigen 2, NOVA2, ANOVA, NOVA3
Tissue Specificity: Brain. Expression restricted to astrocytes.
Background: The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. The encoded protein down-regulates the AKT signaling cascade and can suppress the growth of cervical cancer cells.
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分子量
- 100 kDa
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基因ID
- 55753
抗原
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