NCOR1 抗体 (AA 2301-2400)
Quick Overview for NCOR1 抗体 (AA 2301-2400) (ABIN726515)
抗原
See all NCOR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2301-2400
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预测反应
- Human,Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NC0R1
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
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别名
- NCoR1
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背景
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Synonyms: RIP13, Rxrip13, hCIT529I10, hN CoR, hNCoR, KIAA1047, MGC104216, N CoR, N Cor/SMRT corepressor Rip13, N CoR1, NCOR 1, NCoR, NCOR1, Nuclear receptor co repressor 1, Nuclear receptor corepressor 1, Retinoid X receptor interacting protein 13, thyroid hormone and retinoic acid receptor associated corepressor 1, thyroid hormone- and retinoic acid receptor-associated corepressor 1, TRAC 1, TRAC1, Nuclear Receptor Corepressor NCoR, NCOR1_MOUSE.
Background: Nuclear co-repressor 2 (N-CoR2) gene (NCOR2, previously called silencing mediator for retinoid and thyroid hormone receptor SMRT) is recruited to nuclear and non-nuclear receptors in a large repressing complex containing also N-CoR1, mSin3 and HDACs. This large complex represses transcription in absence of ligand. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Tissue specificity: Ubiquitous. It is belongs to the N-CoR nuclear receptor corepressors family.
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基因ID
- 9611
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途径
- Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
抗原
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