ACAT1 抗体 (AA 34-427)
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Quick Overview for ACAT1 抗体 (AA 34-427) (ABIN7596086)
抗原
See all ACAT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 34-427
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原理
- Human ACAT1 antibody
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纯化方法
- Purified
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免疫原
- Recombinant human ACAT1 (34-427aa) purified from E. coli
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- ACAT1 (Acetyl-CoA Acetyltransferase 1 (ACAT1))
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别名
- ACAT1
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背景
- ACAT1 (acetyl-Coenzyme A acetyltransferase 1) is a 417 amino acid protein. ACAT1 is a mitochondrial enzyme involved in the formation and degradation of ketone bodies and is necessary for the proper metabolic processing of isoleucine. ACAT1 and ACAT2 catalyze the formation of acetoacetyl-CoA from two acetyl-CoA molecules. These enzymes are also capable of the reverse reaction. Defects in ACAT1 are a cause of 3-ketothiolase deficiency. 3-ketothiolase deficiency is an inborn error of isoleucine catabolism characterized by intermittent ketoacidotic attacks associated with unconsciousness. Some patients die during an attack or are mentally retarded.
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NCBI登录号
- NP_000010
抗原
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