MAFK 抗体 (AA 1-156)
Quick Overview for MAFK 抗体 (AA 1-156) (ABIN7596043)
抗原
See all MAFK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-156
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原理
- Human MafK antibody
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纯化方法
- protein-A affinity chromatography
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免疫原
- Recombinant human MAFK (1-156aa) purified from E. coli
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亚型
- IgG2a kappa
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anti-Transcription Factor MafK (MAFK) antibody
MAFK 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 8C5 unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 斑马鱼, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠, 豚鼠, Hamster, 猴, 小鸡, 非洲爪蟾, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- MAFK (Transcription Factor MafK (MAFK))
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别名
- MafK
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背景
- The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locuscontrol regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by thetranscription factor NFE2 (nuclear factor erythroid-2). NFE2 DNA-binding activity consists of aheterodimer containing an 18-kD Maf protein (MafF, MafG or MafK) and p45. Since Maf homodimers lack aputative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize amongthemselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger)basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerizewith Fos and may act as competitive repressors of the NF-E2 transcription factor. The MafK of Maf proteinsis primarily expressed during development in mesenchymal and hematopoietic cells and neurons.
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NCBI登录号
- NP_002351
抗原
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