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EpCAM 抗体 (AA 24-265)

This anti-EpCAM antibody is a 小鼠 单克隆 antibody detecting EpCAM in WB, IF, ELISA 和 ICC. Suitable for 人.
产品编号 ABIN7596020
发货至: 中国

Quick Overview for EpCAM 抗体 (AA 24-265) (ABIN7596020)

抗原

See all EpCAM (EPCAM) 抗体
EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This EpCAM antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

克隆位点

AT36F10
  • 抗原表位

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    AA 24-265

    原理

    Human EpCAM/TROP-1 antibody

    纯化方法

    protein-A affinity chromatography

    免疫原

    Recombinant human EpCAM/TROP-1 (24-265aa) purified from E. coli

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

    别名

    EpCAM/TROP-1

    背景

    Epithelial cell adhesion molecule (EPCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EPCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EPCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EPCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EPCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.

    NCBI登录号

    NP_002345
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