HCN1 抗体 (AA 778-910)
Quick Overview for HCN1 抗体 (AA 778-910) (ABIN7595944)
抗原
See all HCN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 778-910
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原理
- Anti-HCN1 Antibody
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特异性
- No off-targets reported for HCN2
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交叉反应
- Gerbil, 人, 小鼠, Non-Human Primate, 大鼠
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产品特性
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Description: Our Anti-HCN1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N70/28. It is KO validated, detects human, mouse, and rat HCN1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Manufacturer Comment: We produce our HCN1 mouse monoclonal primary antibody from hybridoma clone N70/28. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein amino acids 778-910 (cytoplasmic C-terminus) of rat HCN1 (accession number Q9JKB0), Mouse: 96% identity (128/133 amino acids identical) produced recombinantly in E. Coli
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亚型
- IgG1
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anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody
HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 unconjugated
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (HRP)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 HRP
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (FITC)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 FITC
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (Biotin)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 Biotin
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (PE)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 PE
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (PerCP)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 PerCP
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (APC)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 APC
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (Atto 488)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 Atto 488
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (Atto 594)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 Atto 594
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (Atto 390)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 Atto 390
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应用备注
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Dilution Range: IP: 10 μg
Dilution Range: IHC: 1:500
Dilution Range: ICC: 1:100
Dilution Range: WB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.38
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 24 months
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- HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))
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别名
- HCN1
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背景
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Synonyms: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
Target Description: HCN1 is a member of the hyperpolarization-activated cyclic nucleotide gated channel family, also known as pacemaker channels. This family has a role in rhythmic activity of the heart and firing neurons. HCN channels are made up of four subunits, HCN1-4 and can be formed in multiple combinations. HCN1 is found in the hippocampus, neocortex, and cerebellar cortex of brain. Alterations in this protein have been implicated in the disease early infantile epileptic encephalopathy.
Gene Name Alternatives: Hcn1
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分子量
- 100 kDa
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途径
- Asymmetric Protein Localization
抗原
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