DLG4 抗体 (AA 77-299)
Quick Overview for DLG4 抗体 (AA 77-299) (ABIN7595935)
抗原
See all DLG4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 77-299
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原理
- Anti-PSD-95 Antibody
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特异性
- No off-targets reported for recombinant Chapsyn-110, SAP97 or SAP102
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交叉反应
- 小鸡, 人, 小鼠, Non-Human Primate, 大鼠
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产品特性
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Description: Our Anti-PSD 95 mouse monoclonal primary antibody is produced in-house from hybridoma clone K28/43. It is KO validated, detects chicken, human, mouse, non-human primate, and rat PSD 95, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Manufacturer Comment: We produce our PSD 95 mouse monoclonal primary antibody from hybridoma clone K28/43. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein amino acids 77-299 (PDZ domains 1 and 2) of human PSD-95 (accession number P78352) produced recombinantly in E. Coli
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亚型
- IgG2a
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anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody
DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA, mIHC 宿主: 小鼠 Monoclonal 6G6 unconjugated
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) (C-Term) antibodyDLG4 适用: 大鼠, 人, 小鼠 WB, IHC, ELISA, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibodyDLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 unconjugated
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (HRP)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 HRP
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (FITC)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 FITC
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Biotin)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 Biotin
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (PE)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 PE
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (PerCP)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 PerCP
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (APC)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 APC
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Atto 488)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 Atto 488
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应用备注
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Dilution Range: IP: 5 μg
Dilution Range: IHC: 1:500
Dilution Range: ICC: 1:500
Dilution Range: WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 24 months
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- DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
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别名
- PSD 95
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背景
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Synonyms: Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Target Description: PSD-95 is a member of the MAGUK (membrane associated guanylate kinase) family (which also includes PSD-93, SAP97 and SAP102) and functions as a scaffold protein that can cluster membrane receptors, ion channels, including NMDA receptor subunits, Kv1 potassium channels and Caspr2. The protein is encoded by DLG4, contains hallmark PDZ, SH3 and GuK domains and is found at post synaptic densities where it plays an important role in the formation and maintenance of synaptic junctions (Zhou and Blumberg, 2003). Indeed, overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. Antibodies against PSD95/DLG4 are frequently used in conjunction with pre-synaptic markers to localize synapses by microscopy
Gene Name Alternatives: DLG4 PSD95
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分子量
- 95-110 kDa (varies with cell background due to phosphorylation)
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途径
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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