电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CASK 抗体 (AA 318-415) (FL650)

This anti-CASK antibody is a 小鼠 单克隆 antibody detecting CASK in IHC 和 ICC. Suitable for 人.
产品编号 ABIN7595840
发货至: 中国

Quick Overview for CASK 抗体 (AA 318-415) (FL650) (ABIN7595840)

抗原

See all CASK 抗体
CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

适用

  • 41
  • 29
  • 29
  • 1

宿主

  • 55
  • 6
小鼠

克隆类型

  • 55
  • 6
单克隆

标记

  • 22
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CASK antibody is conjugated to FL650

应用范围

  • 24
  • 18
  • 17
  • 13
  • 13
  • 8
  • 6
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

K56A-50
  • 抗原表位

    • 15
    • 8
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 318-415

    原理

    Anti-CASK Antibody FL650 Conjugate

    特异性

    No off-targets reported

    交叉反应

    小鸡, 人, 小鼠, 大鼠, 非洲爪蟾, 斑马鱼

    产品特性

    Description: Our Anti-CASK mouse monoclonal primary antibody is produced in-house from hybridoma clone K56A/50. It is KO validated, detects chicken, human, mouse, rat, Xenopus, and zebrafish CASK, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

    Manufacturer Comment: We produce our CASK mouse monoclonal primary antibody from hybridoma clone K56A/50. It is great in IHC, ICC and is purified by Protein A chromatography.

    纯化方法

    Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

    纯度

    > 90 % specific antibody

    免疫原

    Fusion protein amino acids 318-415 of rat CASK/Lin2 (accession number Q62915) produced recombinantly in E. Coli

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.09 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

    有效期

    12 months
  • 抗原

    CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

    别名

    CASK

    背景

    Synonyms: Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)

    Target Description: Calcium/Calmodulin-Dependent Serine Protein Kinase or CASK scaffolding protein is encoded by the gene CASK. CASK is a member of the MAGUK (membrane-associated guanylate kinase) protein family. CASK is a a calcium/calmodulin-dependent serine protein kinase. CASK is found in many different tissues including kidney, lung, liver and brain. In the brain, CASK protein is located at synapses. CASK acts as a multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Mutations in this gene are associated with FG syndrome 4, microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability.

    Gene Name Alternatives: CASK LIN2

    分子量

    100 kDa

    途径

    Synaptic Vesicle Exocytosis
You are here:
Chat with us!