GSG2 抗体 (AA 1-798) (FL650)
Quick Overview for GSG2 抗体 (AA 1-798) (FL650) (ABIN7595812)
抗原
See all GSG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-798
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原理
- Anti-Haspin/GSG2 Antibody FL650 Conjugate
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特异性
- No off-targets reported
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交叉反应
- 人
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产品特性
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Description: Our Anti-Haspin/GSG2 mouse monoclonal primary antibody is produced in-house from hybridoma clone N128A/2. It detects human Haspin/GSG2, and is purified by Protein A chromatography. It is great for use in ICC.
Manufacturer Comment: We produce our Haspin/GSG2 mouse monoclonal primary antibody from hybridoma clone N128A/2. It is great in ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein amino acids 1-798 (full-length) of human Haspin (accession number Q8TF76)
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))
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别名
- GSG2
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背景
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Synonyms: Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (H-haspin) (Haploid germ cell-specific nuclear protein kinase)
Target Description: Histone H3 Associated Protein Kinase is encoded by the gene HASPIN. HASPIN is a member of the protein kinase superfamily, Ser/Thr protein kinase family, and the Haspin subfamily. HASPIN is a serine/threonine - protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. HASPIN may act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment, and normal progression through the cell cycle. HASPIN is expressed in the testis, thymus, bone marrow, prostate, intestine, lung, spleen, and lymph node. No diseases were found to be associated with HASPIN.
Gene Name Alternatives: HASPIN GSG2
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分子量
- 90 kDa
抗原
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