SHANK2 抗体 (AA 84-309) (FL594)
Quick Overview for SHANK2 抗体 (AA 84-309) (FL594) (ABIN7595735)
抗原
See all SHANK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 84-309
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原理
- Anti-Shank2 Antibody FL594 Conjugate
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特异性
- No off-targets reported for Shank1 or Shank3
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交叉反应
- 人, 小鼠, 兔, 大鼠
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产品特性
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Description: Our Anti-Shank2 mouse monoclonal primary antibody is produced in-house from hybridoma clone N23B/6. It detects human, mouse, and rat Shank2, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Manufacturer Comment: We produce our Shank2 mouse monoclonal primary antibody from hybridoma clone N23B/6. It is great in IHC, ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein amino acids 84-309 (SH3/PDZ domains) of rat Shank2 (accession number Q9QX74) produced recombinantly in E. Coli
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亚型
- IgG1
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anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody
SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) unconjugated
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (HRP)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) HRP
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (FITC)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) FITC
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Biotin)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) Biotin
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (PE)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) PE
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (PerCP)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) PerCP
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (APC)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) APC
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Atto 594)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) Atto 594
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Atto 488)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) Atto 488
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Atto 390)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) Atto 390
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))
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别名
- Shank2
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背景
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Synonyms: SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (GKAP/SAPAP-interacting protein) (Proline-rich synapse-associated protein 1) (ProSAP1) (SPANK-3)
Target Description: SH3 and multiple ankyrin repeat domains protein 2, or shank 2 is a member of the shank family. Shank 2 binding domains include a SH3 domain, a proline rich domain, and a PDZ domain. Shank 2 is found in kidney, liver tissue, and epithelial cells. In brain, Shank 2 is expressed at the apical cell membrane, cytoplasm, synapse, postsynaptic density, growth cone, and dendritic spine. Some isoforms of shank 2 are expressed during development, while others are expressed in mature tissue. Shank 2 acts as a scaffold protein anchoring and connecting membrane bound receptors, including NMDA and glutamate receptors and other proteins to the cytoskeleton in neurons to enable cell signaling. In this manner, Shank 2 may play a role in synapse formation and dendritic spine maturation. Mutations in the Shank 2 gene have been associated with autism spectrm disorder and blount disease.
Gene Name Alternatives: Shank2 Cortbp1
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分子量
- 160 kDa
抗原
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