MESDC2 抗体 (AA 30-95) (FL594)
Quick Overview for MESDC2 抗体 (AA 30-95) (FL594) (ABIN7595707)
抗原
See all MESDC2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 30-95
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原理
- Anti-MESD Antibody FL594 Conjugate
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特异性
- No off-targets reported
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-MESD mouse monoclonal primary antibody is produced in-house from hybridoma clone N88/12. It detects human, mouse, and rat MESD, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Manufacturer Comment: We produce our MESD mouse monoclonal primary antibody from hybridoma clone N88/12. It is great in IHC, ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein amino acids 30-95 and 118-180 (lacking VSD domain) of mouse MESD (accession number Q9ERE7) produced recombinantly in E. Coli
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亚型
- IgG2b
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anti-Mesoderm Development Candidate 2 (MESDC2) (AA 1-234) antibody
MESDC2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mesoderm Development Candidate 2 (MESDC2) (AA 203-234), (C-Term) antibodyMESDC2 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Mesoderm Development Candidate 2 (MESDC2) antibodyMESDC2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mesoderm Development Candidate 2 (MESDC2) (Internal Region) antibodyMESDC2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mesoderm Development Candidate 2 (MESDC2) (AA 1-234) antibodyMESDC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- MESDC2 (Mesoderm Development Candidate 2 (MESDC2))
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别名
- MESD
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背景
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Synonyms: LRP chaperone MESD (LDLR chaperone MESD) (Mesoderm development candidate 2) (Mesoderm development protein)
Target Description: Mesoderm Development LRP Chaperone is encoded by the gene MESD. MESD is a member of the MESD family. MESD is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). MESD acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. MESD is essential for the specification of embryonic polarity and mesoderm induction. MESD plays an essential role neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4. MESD is expressed in many tissues, but not in skeletal muscles. Diseases associated with MESD include Osteogenesis Imperfecta, Type Xx and Epilepsy, Nocturnal Frontal Lobe, 2.
Gene Name Alternatives: Mesd Mesdc2
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分子量
- 26 kDa
抗原
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