CADM1 抗体 (AA 257-388) (FL594)
Quick Overview for CADM1 抗体 (AA 257-388) (FL594) (ABIN7595704)
抗原
See all CADM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 257-388
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原理
- Anti-SynCAM1 Antibody FL594 Conjugate
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特异性
- No cross-reactivity with SynCAM2 or SynCAM3
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-SynCAM1 mouse monoclonal primary antibody is produced in-house from hybridoma clone L45/30. It detects human, mouse, and rat SynCAM1, and is purified by Protein A chromatography. It is great for use in ICC.
Manufacturer Comment: We produce our SynCAM1 mouse monoclonal primary antibody from hybridoma clone L45/30. It is great in ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein amino acids 257-388 of mouse SynCAM1 (accession number Q8R5M8), recognizes 1.4b isoform only (epitope narrowed to GLTQLPNSAEELDSEDLS) produced recombinantly in E. Coli
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- CADM1 (Cell Adhesion Molecule 1 (CADM1))
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别名
- SynCAM1
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背景
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Synonyms: Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)
Target Description: SynCAM1 cell adhesion molecule, Immunoglobulin superfamily member 4 (IgSF4), or Nectin-like protein 2 (NECL-2) is encoded by the gene CADM1 and is a member of the Immunoglobulin-like Cell Adhesion Molecules family. SynCam1 is a cell adhesion molecule involved in many cell processes including the mediation of cell-cell adhesion and assembly, neuronal migration axon growth and differentiation. SynCAM1 is expressed in many tissue types including, brain, lung, kidney, heart, spleen and liver. Diseases associated with this gene include Retroperitoneal Fibrosis and Neuromyelitis Optica Spectrum Disorder.
Gene Name Alternatives: Cadm1 Igsf4 Necl2 Ra175 Syncam SynCam1 Tslc1
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分子量
- 50 kDa
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation
抗原
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