HSPA9 抗体 (AA 551-766) (FL550)
Quick Overview for HSPA9 抗体 (AA 551-766) (FL550) (ABIN7595595)
抗原
See all HSPA9 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 551-766
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原理
- Anti-Mortalin/GRP75 Antibody FL550 Conjugate
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特异性
- No off-targets reported
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交叉反应
- 人, 小鼠, Non-Human Primate, 大鼠
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产品特性
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Description: Our Anti-Mortalin/GRP75 mouse monoclonal primary antibody is produced in-house from hybridoma clone N52A/42. It detects human, mouse, and rat Mortalin/GRP75, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Manufacturer Comment: We produce our Mortalin/GRP75 mouse monoclonal primary antibody from hybridoma clone N52A/42. It is great in IHC, ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Identified as off-target mAb in screen for anti-Salm2 NeuroMabs (immunogen was fusion protein amino acids 551-766 of mouse SALM2). Target identified as Mortalin/Grp75 by LC-MS/MS analysis of protein immunopurified from rat brain using N52A/42.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- HSPA9 (Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9))
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别名
- GRP75
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背景
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Synonyms: Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (Peptide-binding protein 74) (PBP74) (p66 MOT)
Target Description: Mitochondrial stress-70 protein or Mortalin/GRP75 is encoded by the gene HSPA9. Mortalin is a chaperone protein and plays a role in cell proliferation, stress response and mitochondria maintenance. It is widely expressed in tissues in mitochondria, endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. Diseases associated with this gene include Even-Plus Syndrome and Sideroblastic Anemia 4.
Gene Name Alternatives: Hspa9 Grp75 Hsp74 Hspa9a
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分子量
- 75 kDa
抗原
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